Karen J. Sherman, PhD, MPH, is an epidemiologist and clinical trialist. Her research interests include:
She has led or participated in groundbreaking studies of various non-pharmacological therapies for chronic low back pain, including acupuncture, massage, meditation, and yoga.
Dr. Sherman has collaborated with investigators at Kaiser Permanente Washington Health Research Institute (KPWHRI) and elsewhere across a range of disciplines, including clinical trials of CIH therapies for cancer, mood disorders, and menopause. Her work on building the evidence base for contextual factors related to care tries to find ways to bring greater healing into the primary care encounter. Dr. Sherman hopes her work will encourage more focus on the intricate connections between mind and body—and on helping patients seize the power of this connection to pursue better health and healing at all phases of life, including older age. Her work is rigorous, designed to answer practical questions, and intended to have impacts on the whole person.
Dr. Sherman is a senior scientific investigator at KPWHRI and an affiliate professor of epidemiology at the University of Washington (UW) School of Public Health. Her doctorate is in behavioral biology from Cornell University, and her MPH is in epidemiology from the UW. She has served as a reviewer for dozens of medical journals and granting institutions, and has sat on editorial boards for numerous CIH journals.
Utilization; role of complementary and alternative medicine in health care; acupuncture; massage; meditation; tai chi; yoga; fibromyalgia; menopause; back pain; neck pain; anxiety disorders
Chronic back pain; diabetes care; self-management
Alternative therapies for anxiety disorders
Alternative therapies for menopause
Communication; patient expectations; patient education
Saper RB, Lemaster C, Delitto A, Sherman KJ, Herman PM, Sadikova E, Stevans J, Keosaian JE, Cerrada CJ, Fernia AL, Roseen EJ, Gardiner P, Gergen-Barnett K, Faulkner C, Weinberg J. Yoga, physical therapy, or education for chronic low back pain: a randomized noninferiority trial. Ann Intern Med. 2017 Jun 20. doi: 10.7326/M16-2579. [Epub ahead of print]. PubMed
MacPherson H, Vertosick EA, Foster NE, Lewith G, Linde K, Sherman KJ, Witt CM, Vickers AJ. The persistence of the effects of acupuncture after a course of treatment: a meta-analysis of patients with chronic pain. Pain. 2017 May;158(5):784-793. doi: 10.1097/j.pain.0000000000000747. PubMed
Cherkin DC, Anderson ML, Sherman KJ, Balderson BH, Cook AJ, Hansen KE, Turner JA. Two-year follow-up of a randomized clinical trial of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care for chronic low back pain. JAMA. 2017;317(6):642-644. doi: 10.1001/jama.2016.17814. PubMed
Turner JA, Anderson ML, Balderson BH, Cook AJ, Sherman KJ, Cherkin DC. Mindfulness-based stress reduction and cognitive-behavioral therapy for chronic low back pain: similar effects on mindfulness, catastrophizing, self-efficacy, and acceptance in a randomized controlled trial. Pain. 2016 Nov;157(11):2434-2444.doi:10.1097/j.pain.0000000000000635. PubMed
Jones SM, Lange J, Turner J, Cherkin D, Ritenbaugh C, Hsu C, Berthoud H, Sherman K. Development and validation of the EXPECT questionnaire: assessing patient expectations of outcomes of complementary and alternative medicine treatments for chronic pain. J Altern Complement Med. 2016 Nov;22(11):936-946. Epub 2016 Sep 30. PubMed
Rundell SD, Sherman KJ, Heagerty PJ, Mock CN, Dettori NJ, Comstock BA, Avins AL, Nedeljkovic SS, Nerenz DR, Jarvik JG. Predictors of persistent disability and back pain in older adults with a new episode of care for back pain. Pain Med. 2017 Jun 1;18(6):1049-1062. doi: 10.1093/pm/pnw236. PubMed
Cherkin DC, Sherman KJ, Turner JA. Mindfulness-based stress reduction vs cognitive behavioral therapy for chronic low back pain-reply. JAMA. 2016 Aug 9;316(6):663-4. doi: 10.1001/jama.2016.7951. No abstract available. PubMed
Cherkin DC, Sherman KJ, Balderson BH, Cook AJ, Anderson ML, Hawkes RJ, Hansen KE, Turner JA. Effect of mindfulness-based stress reduction vs cognitive behavioral therapy or usual care on back pain and functional limitations in adults with chronic low back pain: a randomized clinical trial. JAMA. 2016 Mar 22-29;315(12):1240-9. doi: 10.1001/jama.2016.2323. PubMed
Keosaian JE, Lemaster CM, Dresner D, Godersky ME, Paris R, Sherman KJ, Saper RB. "We're all in this together": A qualitative study of predominantly low income minority participants in a yoga trial for chronic low back pain. Complement Ther Med. 2016 Feb;24:34-9. doi: 10.1016/j.ctim.2015.11.007. Epub 2015 Dec 2. PubMed
Saper RB, Lemaster CM, Elwy AR, Paris R, Herman PM, Plumb DN, Sherman KJ, Groessl EJ, Lynch S, Wang S, Weinberg J. Yoga versus education for Veterans with chronic low back pain: study protocol for a randomized controlled trial. Trials. 2016 Apr 29;17(1):224. doi: 10.1186/s13063-016-1321-5. PubMed
Drs. DeBar, Bradley, and Sherman will lead projects in major new initiative to tackle national opioid crisis.
Risk-reduction initiative for chronic opioid therapy sustains patient-doctor trust, Dr. Karen Sherman finds.
Kaiser Permanente researchers Drs. Daniel Cherkin, Karen Sherman, and Andrew Avins produced much of evidence in ICER report.
Read it in News and Events.
AARP, Feb. 6, 2020
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.