Diana S.M. Buist, PhD, MPH

“My research goal is to gather solid evidence and to use it to improve patient care by increasing benefits and decreasing harms.”

Diana S.M. Buist, PhD, MPH

Senior Investigator and Director of Research and Strategic Partnerships, Kaiser Permanente Washington Health Research Institute

Biography

Diana Buist, PhD, MPH, is an epidemiologist and health services researcher with extensive experience conducting comparative effectiveness research. Her work focuses on reducing harms and increasing benefits for patients in the area of cancer screening and outcomes spanning across patient, provider, and system factors.

Dr. Buist has an extensive record of practical research that has led to many efforts to improve care, including the development and refinement of national breast cancer screening guidelines. She has been conducting research within Kaiser Permanente Washington for more than 20 years and is a strong believer in patient-centered care and the important role patients play in improving the value and quality of health care. Dr. Buist is involved in several studies aimed at reducing low-value care in diverse settings, including a Robert Wood Johnson Foundation-funded project to develop an action planning framework to facilitate changes that improve the value of health care

She also has a long history collaborating with external researchers, including helping lead two large national research consortia focused on improving cancer screening and outcomes: the National Cancer Institute’s Breast Cancer Surveillance Consortium and the Health Care Systems Cancer Research Network (CRN). Her extensive experience working with these diverse data in longitudinal studies and randomized trials in clinical systems puts Dr. Buist in a unique position to examine screening, care, and outcomes in health systems across the country.

Dr. Buist contributes to a variety of other projects at KPWHRI, including:

  • a pragmatic clinical trial of home testing for HPV among women overdue for cervical cancer screening,
  • optimizing long-term outcomes among women with a personal history of breast cancer,
  • evaluating the harms and benefits of different work-up intensities for incidentally detected lung nodules, and
  • evaluating the harms and benefits of breast cancer screening in older women.

As KPWHRI’s director of research and strategic partnerships, Dr. Buist focuses on building enduring strategic external partnerships to enhance the Institute’s mission and capitalize on our unique strengths. She is an affiliate professor in the Departments of Epidemiology and Health Services at the University of Washington School of Public Health and affiliate member at Fred Hutchinson Cancer Research Center. She has also served as a senior scholar in residence with AcademyHealth. The former co-director of the CRN Scholars Program, Dr. Buist enjoys sharing her expertise by mentoring junior faculty and PhD and MPH candidates and teaching courses in clinical outcomes research internationally through the American Thoracic Society.

RESEARCH INTERESTS AND EXPERIENCE

  • Cancer

    Cancer screening and prevention; outreach and primary care prevention; comparative effectiveness; cost transparency; surveillance; secondary prevention; breast cancer treatment; breast cancer screening; outcomes following cancer diagnosis; cancer survivorship; provider variability in care

  • Preventive Medicine

    Cancer prevention and control; quality of care; preventive care; high-value care; consumer engagement in preventive medicine; systematic reviews

  • Women's Health

    Cancer prevention and control

  • Health Services & Economics

     

Recent publications

Lee JM, Abraham L, Lam DL, Buist DSM, Kerlikowske K, Miglioretti DL, Houssami N, Lehman CD, Henderson LM, Hubbard RA. Cumulative risk distribution for interval invasive second breast cancers after negative surveillance mammography. J Clin Oncol. 2018 May 2:JCO2017768267. doi: 10.1200/JCO.2017.76.8267. [Epub ahead of print]. PubMed

Brentnall AR, Cuzick J, Buist DSM, Bowles EJA. Long-term accuracy of breast cancer risk assessment combining classic risk factors and breast density. JAMA Oncol. 2018 Apr 5:e180174. doi: 10.1001/jamaoncol.2018.0174. [Epub ahead of print]. PubMed

Onega T, Zhu W, Weiss JE, Goodrich M, Tosteson ANA, DeMartini W, Virnig BA, Henderson LM, Buist DSM, Wernli KJ, Kerlikowske K, Hubbard RA. Preoperative breast MRI and mortality in older women with breast cancer. Breast Cancer Res Treat. 2018 Mar 7. pii: 10.1007/s10549-018-4732-z. doi: 10.1007/s10549-018-4732-z. [Epub ahead of print]. PubMed

Buist DSM, Abraham L, Lee CI, Lee JM, Lehman C, O'Meara ES, Stout NK, Henderson LM, Hill D, Wernli KJ, Haas JS, Tosteson ANA, Kerlikowske K, Onega T. Breast biopsy intensity and findings following breast cancer screening in women with and without a personal history of breast cancer. JAMA Intern Med. 2018 Feb 12. pii: 2672204. doi: 10.1001/jamainternmed.2017.8549. [Epub ahead of print]. PubMed

Braithwaite D, Miglioretti DL, Zhu W, Demb J, Trentham-Dietz A, Sprague B, Tice JA, Onega T, Henderson LM, Buist DSM, Ziv E, Walter LC, Kerlikowske K. Family history and breast cancer risk among older women in the Breast Cancer Surveillance Consortium cohort. JAMA Intern Med. 2018 Feb 12. pii: 2672205. doi: 10.1001/jamainternmed.2017.8642. [Epub ahead of print]. PubMed

Roth JA, Carter-Harris L, Brandzel S, Buist DSM, Wernli KJ. A qualitative study exploring patient motivations for screening for lung cancer. PLoS One. 2018 Jul 5;13(7):e0196758. doi: 10.1371/journal.pone.0196758. eCollection 2018. PubMed

Onega T, Weiss JE, Goodrich ME, Zhu W, DeMartini WB, Kerlikowske K, Ozanne E, Tosteson ANA, Henderson LM, Buist DSM, Wernli KJ, Herschorn SD, Hotaling E, O'Donoghue C, Hubbard R. Relationship between preoperative breast MRI and surgical treatment of non-metastatic breast cancer. J Surg Oncol. 2017 Dec;116(8):1008-1015. doi: 10.1002/jso.24796. Epub 2017 Nov 11. PubMed

Winer RL, Tiro JA, Miglioretti DL, Thayer C, Beatty T, Lin J, Gao G, Kimbel K, Buist DSM. Rationale and design of the HOME trial: a pragmatic randomized controlled trial of home-based human papillomavirus (HPV) self-sampling for increasing cervical cancer screening uptake and effectiveness in a U.S. healthcare system. Contemp Clin Trials. 2017 Nov 4. pii: S1551-7144(17)30453-6. doi: 10.1016/j.cct.2017.11.004. [Epub ahead of print]. PubMed

Shiyanbola OO, Arao RF, Miglioretti DL, Sprague BL, Hampton JM, Stout NK, Kerlikowske K, Braithwaite D, Buist DSM, Egan KM, Newcomb PA, Trentham-Dietz A. Emerging trends in family history of breast cancer and associated risk. Cancer Epidemiol Biomarkers Prev. 2017 Dec;26(12):1753-1760. doi: 10.1158/1055-9965.EPI-17-0531. Epub 2017 Oct 6. PubMed

Lee JM, Ichikawa L, Valencia E, Miglioretti DL, Wernli K, Buist DSM, Kerlikowske K, Henderson LM, Sprague BL, Onega T, Rauscher GH, Lehman CD. Performance benchmarks for screening breast MR imaging in community practice. Radiology. 2017 Oct;285(1):44-52. doi: 10.1148/radiol.2017162033. Epub 2017 Jun 5. PubMed

 

cancer

What to expect after a screening breast MRI vs. mammography alone

Diana Buist and BCSC find screening MRI leads to more biopsies, finding fewer cancers, regardless of personal history of breast cancer: JAMA Internal Medicine.

Read it in Healthy Findings

Health Research Meeting

Seattle to host premier health services research meeting

Thousands of national health care and policy experts will attend the 2018 AcademyHealth Annual Research Meeting. Submit abstracts by January 11.

Read it in Healthy Findings

recent News

KPWHRI shares in $17 million grant to improve breast screening

National Cancer Institute support continues nation's largest collection of breast imaging data and funds three studies to personalize screening.

Read it in News and Events

Preventive Medicine

How to boost rates of cancer screening among Latinas and Black women?

Kaiser Permanente Washington patients suggested several potential solutions to Susan Carol Bradford and colleagues.

Read our Healthy Findings blog article, published in Healthcare in America.

KPWHRI In the Media

The Digital Mammography DREAM Challenge

$1.2M crowdsourced contest aims to improve breast-cancer detection through deep machine learning

GeekWire, Aug. 25, 2016

Breast Cancer Surveillance

Kaiser Permanente Washington Breast Cancer Surveillance Registry

Kaiser Permanente Washington has been part of the national Breast Cancer Surveillance Consortium since 1994. Learn about the Kaiser Permanente Washington Breast Cancer Surveillance Registry here.