Diana S.M. Buist, PhD, MPH

“My research goal is to gather solid evidence and to use it to improve patient care by increasing benefits and decreasing harms.”

Diana S.M. Buist, PhD, MPH

Senior Investigator and Director of Research and Strategic Partnerships, Kaiser Permanente Washington Health Research Institute

Biography

Diana Buist, PhD, MPH, is an epidemiologist and health services researcher with extensive experience conducting comparative effectiveness research. Her work focuses on reducing harms and increasing benefits for patients in the area of cancer screening and outcomes spanning across patient, provider, and system factors.

Dr. Buist has an extensive record of practical research that has led to many efforts to improve care, including the development and refinement of national breast cancer screening guidelines and their implementation within Kaiser Permanente Washington. She has been conducting research within Kaiser Permanente Washington for more than 20 years and is a strong believer in patient-centered care and the important role patients play in improving the value and quality of health care. Dr. Buist is involved in several studies aimed at providing high-value health care that provides patients and their providers with information on the expected benefits and harms of cancer screening and treatment strategies.

Dr. Buist also has a long history collaborating with external researchers, including helping lead two large national research consortia focused on improving cancer screening and outcomes: the National Cancer Institute’s Breast Cancer Surveillance Consortium and the Cancer Research Network of the Health Care Systems Research Network. Her extensive experience working with diverse data from these consortia in longitudinal studies and randomized trials in clinical systems puts Dr. Buist in a unique position to examine screening, care, and outcomes in health systems across the country.

As Kaiser Permanente Washington Health Research Institute (KPWHRI) Director of Research and Strategic Partnerships, Dr. Buist works with other Kaiser Permanente regions, our local academic partners, and other external collaborators to build enduring strategic partnerships to enhance KPWHRI’s mission, align with KPWHRI faculty research priorities, and capitalize on our unique strengths in ways that are consistent with our mission.

Dr. Buist contributes to a variety of other projects at KPWHRI, including:

  • conducting a pragmatic clinical trial of home testing for human papilloma virus, or HPV, among women overdue for cervical cancer screening
  • optimizing long-term outcomes among women with a personal history of breast cancer through studying second breast events and second cancers associated with initial breast cancer, and investigating radiation therapy, breast density, tumor biology, and surveillance strategies for these women
  • identifying screening strategies that detect breast cancer early, minimize harms, and reach diverse communities
  • understanding the shared decision-making process for lung cancer screening from the patient and provider perspectives to help inform individuals about the harms and benefits of undergoing screening
  • investigating how artificial intelligence can be used in cancer imaging for risk prediction and/or early detection
  • evaluating the harms and benefits of different work-up intensities for incidentally detected lung nodules
  • training individuals in how to conduct learning health system research.

Dr. Buist is also an affiliate professor in the Departments of Epidemiology and Health Services at the University of Washington School of Public Health and an affiliate member at Fred Hutchinson Cancer Research Center. She enjoys sharing her expertise by mentoring junior faculty and PhD and MPH candidates and teaching courses.

RESEARCH INTERESTS AND EXPERIENCE

  • Cancer

    Cancer screening and prevention; outreach and primary care prevention; comparative effectiveness; cost transparency; surveillance; secondary prevention; breast cancer treatment; breast cancer screening; outcomes following cancer diagnosis; cancer survivorship; provider variability in care

  • Preventive Medicine

    Cancer prevention and control; quality of care; preventive care; high-value care; consumer engagement in preventive medicine; systematic reviews

  • Women's Health

    Cancer prevention and control

  • Health Services & Economics

     

 

Recent publications

Parchman ML, Henrikson NB, Blasi PR, Buist DS, Penfold R, Austin B, Ganos EH. Taking action on overuse: creating the culture for change. Healthc (Amst). 2016 Nov 10. pii: S2213-0764(16)30167-1. doi: 10.1016/j.hjdsi.2016.10.005. [Epub ahead of print]. PubMed

Farjah F, Halgrim S, Buist DS, Gould MK, Zeliadt SB, Loggers ET, Carrell DS. An automated method for identifying individuals with a lung nodule can be feasibly implemented across health systems. EGEMS (Wash DC). 2016 Aug 26;4(1):1254. doi: 10.13063/2327-9214.1254. eCollection 2016. PubMed

Goodrich ME, Weiss J, Onega T, Balch SL, Buist DS, Kerlikowske K, Henderson LM, Hubbard RA. The role of preoperative magnetic resonance imaging in the assessment and surgical treatment of interval and screen-detected breast cancer in older women. lid - 10.1111/tbj.12651 [doi] Breast J. 2016 Nov;22(6):616-622. doi: 10.1111/tbj.12651. Epub 2016 Aug 23. PubMed

Loggers ET, Buist DS, Gold LS, Zeliadt S, Hunter Merrill R, Etzioni R, Ramsey SD, Sullivan SD, Kessler L. Advanced imaging and receipt of guideline concordant care in women with early stage breast cancer. Int J Breast Cancer. 2016;2016:2182985. doi: 10.1155/2016/2182985. Epub 2016 Jul 25. PubMed

Drescher CW, Beatty JD, Resta R, Andersen MR, Watabayashi K, Thorpe J, Hawley S, Purkey H, Chubak J, Hanson N, Buist DS, Urban N. The effect of referral for genetic counseling on genetic testing and surgical prevention in women at high risk for ovarian cancer: results from a randomized controlled trial. Cancer. 2016 Jul 22. doi: 10.1002/cncr.30190. [Epub ahead of print]. PubMed

Elmore JG, Cook AJ, Bogart A, Carney PA, Geller BM, Taplin SH, Buist DS, Onega T, Lee CI, Miglioretti DL. Radiologists' interpretive skills in screening vs. diagnostic mammography: are they related? Clin Imaging. 2016 Jul 1;40(6):1096-1103. doi: 10.1016/j.clinimag.2016.06.014. [Epub ahead of print]. PubMed

Ozanne EM, Weiss JE, Onega T, DeMartini W, Kerlikowske K, Buist DS, Henderson L, Hubbard RA, Goodrich M, Tosteson AN, Virnig BA, O'Donoghue C. Locoregional treatment of breast cancer in women with and without preoperative magnetic resonance imaging. Am J Surg. 2016 Jun 12. pii: S0002-9610(16)30286-0. doi: 10.1016/j.amjsurg.2016.03.014. [Epub ahead of print]. PubMed

Onega T, Weiss JE, Buist DS, Tosteson AN, Henderson LM, Kerlikowske K, Goodrich ME, O'Donoghue C, Wernli KJ, DeMartini WB, Virnig BA, Bennette CS, Hubbard RA. Breast MRI in the diagnostic and preoperative workup among Medicare beneficiaries with breast cancer. Med Care. 2016 Apr 22. [Epub ahead of print]. PubMed

Chubak J, Whitlock EP, Williams SB, Kamineni A, Burda BU, Buist DS, Anderson ML. Aspirin for the prevention of cancer incidence and mortality: systematic evidence reviews for the U.S. Preventive Services Task Force. Ann Intern Med. 2016 Apr 12. doi: 10.7326/M15-2117. [Epub ahead of print]. PubMed

Bowles EJ, Gao H, Brandzel S, Bradford SC, Buist DS. Comparative effectiveness of two outreach strategies for cervical cancer screening. Prev Med. 2016 Jan 25. pii: S0091-7435(16)00030-X. doi: 10.1016/j.ypmed.2016.01.016. [Epub ahead of print]. PubMed

 

cancer research

SusanKarenDianneMary-1col.jpg

Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

Researcher profile

Diana Buist and family in the snow

What drives Diana Buist to study breast cancer screening?

Kaiser Permanente Share profiles longtime KPWHRI investigator and director of research and strategic partnerships.

Read it in News and Events.

Breast Cancer Surveillance

Kaiser Permanente Washington Breast Cancer Surveillance Registry

Kaiser Permanente Washington has been part of the national Breast Cancer Surveillance Consortium since 1994. Learn about the Kaiser Permanente Washington Breast Cancer Surveillance Registry here.

mentorship at kpwhri

Ashley Glass with her mentor Deborah King

Annual mentorship award honors Deborah King and Dr. Diana Buist

Every year the KPWHRI award recognizes two individuals who provide outstanding service in promoting the career development of others.

CATALyST

2018 CATALyST Scholars

Four CATALyST scholars selected to train as learning health system scientists

KP Washington joins forces with UW, WSU, and the VA to train scientists in transforming health care.
 

preventative care

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Cervical cancer screening study explores home-based options

Could at-home kits help save more lives? Drs. Diana Buist and Rachel Winer are on a journey to find out.