Diana S.M. Buist, PhD, MPH

Buist_Diana_S_205x293.jpg

“My research goal is to gather solid evidence and to use it to improve patient care by increasing benefits and decreasing harms.”

Diana S.M. Buist, PhD, MPH

Senior Investigator and Director of Research and Strategic Partnerships, Kaiser Permanente Washington Health Research Institute

Twitter: @dianabuist

Biography

Diana Buist, PhD, MPH, is an epidemiologist and health services researcher with extensive experience conducting comparative effectiveness research. Her work focuses on reducing harms and increasing benefits for patients in the area of cancer screening and outcomes spanning across patient, provider, and system factors.

Dr. Buist has an extensive record of practical research that has led to many efforts to improve care, including the development and refinement of national breast cancer screening guidelines and their implementation within Kaiser Permanente Washington. She has been conducting research within Kaiser Permanente Washington for more than 20 years and is a strong believer in patient-centered care and the important role patients play in improving the value and quality of health care. Dr. Buist is involved in several studies aimed at providing high-value health care that provides patients and their providers with information on the expected benefits and harms of cancer screening and treatment strategies.

Dr. Buist also has a long history collaborating with external researchers, including helping lead two large national research consortia focused on improving cancer screening and outcomes: the National Cancer Institute’s Breast Cancer Surveillance Consortium and the Cancer Research Network of the Health Care Systems Research Network. Her extensive experience working with diverse data from these consortia in longitudinal studies and randomized trials in clinical systems puts Dr. Buist in a unique position to examine screening, care, and outcomes in health systems across the country.

As Kaiser Permanente Washington Health Research Institute (KPWHRI) Director of Research and Strategic Partnerships, Dr. Buist works with other Kaiser Permanente regions, our local academic partners, and other external collaborators to build enduring strategic partnerships to enhance KPWHRI’s mission, align with KPWHRI faculty research priorities, and capitalize on our unique strengths in ways that are consistent with our mission.

Dr. Buist contributes to a variety of other projects at KPWHRI, including:

  • conducting a pragmatic clinical trial of home testing for human papilloma virus, or HPV, among women overdue for cervical cancer screening
  • optimizing long-term outcomes among women with a personal history of breast cancer through studying second breast events and second cancers associated with initial breast cancer, and investigating radiation therapy, breast density, tumor biology, and surveillance strategies for these women
  • identifying screening strategies that detect breast cancer early, minimize harms, and reach diverse communities
  • understanding the shared decision-making process for lung cancer screening from the patient and provider perspectives to help inform individuals about the harms and benefits of undergoing screening
  • investigating how artificial intelligence can be used in cancer imaging for risk prediction and/or early detection
  • evaluating the harms and benefits of different work-up intensities for incidentally detected lung nodules
  • training individuals in how to conduct learning health system research.

Dr. Buist is also an affiliate professor in the Departments of Epidemiology and Health Services at the University of Washington School of Public Health and an affiliate member at Fred Hutchinson Cancer Research Center. She enjoys sharing her expertise by mentoring junior faculty and PhD and MPH candidates and teaching courses.

RESEARCH INTERESTS AND EXPERIENCE

  • Cancer

    Cancer screening and prevention; outreach and primary care prevention; comparative effectiveness; cost transparency; surveillance; secondary prevention; breast cancer treatment; breast cancer screening; outcomes following cancer diagnosis; cancer survivorship; provider variability in care

  • Preventive Medicine

    Cancer prevention and control; quality of care; preventive care; high-value care; consumer engagement in preventive medicine; systematic reviews

  • Women's Health

    Cancer prevention and control

  • Health Services & Economics

     

 

Recent publications

Miglioretti DL, Zhu W, Kerlikowske K, Sprague BL, Onega T, Buist DS, Henderson LM, Smith RA. Breast tumor prognostic characteristics and biennial vs annual mammography, age, and menopausal status. JAMA Oncol. 2015 Nov 1;1(8):1069-77. doi: 10.1001/jamaoncol.2015.3084.

Lehman C, Wellman RD, Buist DS, Kerlikowske K, Tosteson AN, Miglioretti DL. Diagnostic accuracy of digital screening mammography with and without computer-aided detection. JAMA Intern Med. 2015 Sep 28:1-10. doi: 10.1001/jamainternmed.2015.5231. [Epub ahead of print].

Chubak J, Kamineni A, Buist DSM, Anderson ML, Whitlock EP. Aspirin use for the prevention of colorectal cancer: an updated systematic evidence review for the U.S. Preventive Services Task Force. Rockville (MD): Agency for Healthcare Research and Quality (US); 2015 Sep. Report No.: 15-05228-EF-1. U.S. Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews.

Weinmann S, Williams AE, Kamineni A, Buist DS, Masterson EE, Stout NK, Stark A, Ross TR, Owens CL, Field TS, Doubeni CA. Cervical cancer screening and follow-up in 4 geographically diverse US health care systems, 1998 through 2007. Cancer. 2015 Sep 1;121(17):2976-83. doi: 10.1002/cncr.29445. Epub 2015 May 18. PubMed

Falk RT, Dallal CM, Lacey JV Jr, Bauer DC, Buist DS, Cauley JA, Hue TF, LaCroix AZ, Tice JA, Pfeiffer RM, Xu X, Veenstra TD, Brinton LA. Estrogen metabolites are not associated with colorectal cancer risk in postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1419-22. doi: 10.1158/1055-9965.EPI-15-0541. Epub 2015 Jun 23. PubMed

Onega T, Goldman LE, Walker RL, Miglioretti DL, Buist DS, Taplin S, Geller BM, Hill DA, Smith-Bindman R. Facility mammography volume in relation to breast cancer screening outcomes. J Med Screen. 2016 Mar;23(1):31-7. doi: 10.1177/0969141315595254. Epub 2015 Aug 11. PubMed

Jackson SL, Abraham L, Miglioretti DL, Buist DS, Kerlikowske K, Onega T, Carney PA, Sickles EA, Elmore JG. Patient and radiologist characteristics associated with accuracy of two types of diagnostic mammograms. AJR Am J Roentgenol. 2015;205(2):456-63. doi: 10.2214/AJR.14.13672. PubMed

Lee JM, Buist DS, Houssami N, Dowling EC, Halpern EF, Gazelle GS, Lehman CD, Henderson LM, Hubbard RA. Five-year risk of interval-invasive second breast cancer. J Natl Cancer Inst. 2015 Apr 22;107(7). pii: djv109. doi: 10.1093/jnci/djv109. Print 2015. PubMed

Jacobsen KK, Abraham L, Buist DS, Hubbard RA, O'Meara ES, Sprague BL, Kerlikowske K, Vejborg I, Von Euler-Chelpin M, Njor SH. Comparison of cumulative false-positive risk of screening mammography in the United States and Denmark. Cancer Epidemiol. 2015 May 23. pii: S1877-7821(15)00103-4. doi: 10.1016/j.canep.2015.05.004. [Epub ahead of print]. PubMed

Adams KF, Johnson EA, Chubak J, Kamineni A, Doubeni CA, Buist DS, Williams AE, Weinmann S, Doria-Rose VP, Rutter CM. Development of an algorithm to classify colonoscopy indication from coded health care data. EGEMS. (Wash DC). 2015 May 18;3(1):1171. doi: 10.13063/2327-9214.1171. eCollection 2015.

 

news

CATALyST-Scholars-2020_1col.jpg

CATALyST Program selects 2 new K12 Scholars

The early-career scientists will receive 3 years of intensive training in Learning Health System research.

news

CATALyST-K12-Update_1col.jpg

CATALyST adds scholar positions for learning health systems research

Admissions open for two new trainees as current scholars advance their projects.

cancer screening

Buist-HPV-Home-Test-infographic_1col.jpg

Mailing home HPV test may offer alternative to Pap screen

Dr. Diana Buist and team reflect on HOME trial showing 50 percent screening boost in underscreened women.

birnbaum award

Birnbaum-2019-Awardee-HOME_1col.jpg

HOME Trial Team wins 2019 Birnbaum Award

Interdisciplinary group shows that home-based HPV tests can boost cervical cancer screening for women at high risk.

Breast Cancer Surveillance

Kaiser Permanente Washington Breast Cancer Surveillance Registry

Kaiser Permanente Washington has been part of the national Breast Cancer Surveillance Consortium since 1994. Learn about the Kaiser Permanente Washington Breast Cancer Surveillance Registry here.

cancer research

SusanKarenDianneMary-1col.jpg

Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

KPWHRI In the Media

Mailing home HPV tests may provide alternative to Pap screening

Self-testing for cervical cancer increases screening rates

HealthDay, Nov 8, 2019