Michael Jackson, PhD, MPH

“Kaiser Permanente Washington gives us nearly unlimited potential to address vaccine effectiveness and safety questions of national and international importance.”

Michael L. Jackson, PhD, MPH

Associate Investigator, Kaiser Permanente Washington Health Research Institute


Michael L. Jackson, PhD, MPH’s research focuses on understanding how infectious diseases spread, and on designing and evaluating interventions such as vaccination programs. Dr. Jackson is the Kaiser Permanente Washington Health Research Institute (KPWHRI) principal investigator for the United States Influenza Vaccine Effectiveness Network. This Network aims to provide ongoing evaluations of the U.S. influenza vaccination program. Dr. Jackson uses data from this Network to study influenza vaccine effectiveness, to estimate the burden of disease caused by influenza, and to advance the methodology of vaccine effectiveness studies. He also uses mathematical models to predict the impact of vaccination programs on the spread of infectious diseases such as Haemophilus influenza type b (Hib) and Neisseria meningitidis.

Dr. Jackson is a co-investigator on the Vaccine Safety Datalink (VSD) Project. The VSD, a collaboration among nine U.S. managed care organizations and the Centers for Disease Control and Prevention (CDC), is the world’s premier system for post-licensure studies of vaccine safety. As a VSD co-investigator, Dr. Jackson leads studies of the safety of childhood immunizations and develops methods for using managed care data for vaccine safety studies.

While studying for his PhD at the University of Washington, Dr. Jackson was a graduate research associate with KPWHRI from 2002 to 2007, and then a postdoctoral fellow at KPWHRI from 2007 to 2008. He then spent two years as an Epidemic Intelligence Service (EIS) officer with the CDC in Atlanta. As an EIS officer, Dr. Jackson helped lead investigations of whooping cough outbreaks and of the 2009 influenza pandemic. He also designed and oversaw an enhanced surveillance system for invasive Hib disease in the U.S. during the 2008–2009 shortage of Hib vaccines. He returned to KPWHRI as an assistant investigator in 2010.

Research interests and experience




Recent publications

Jackson ML, Phillips CH, Benoit J, Kiniry E, Madziwa L, Nelson JC, Jackson LA. The impact of selection bias on vaccine effectiveness estimates from test-negative studies. Vaccine. 2017 Dec 15. pii: S0264-410X(17)31775-9. doi: 10.1016/j.vaccine.2017.12.022. [Epub ahead of print]. PubMed

Jackson ML, Phillips CH, Benoit J, Jackson LA, Gaglani M, Murthy K, McLean HQ, Belongia EA, Malosh R, Zimmerman R, Flannery B. Burden of medically attended influenza infection and cases averted by vaccination - United States, 2013/14 through 2015/16 influenza seasons. Vaccine. 2017 Dec 14. pii: S0264-410X(17)31755-3. doi: 10.1016/j.vaccine.2017.12.014. [Epub ahead of print]. PubMed

Daley MF, Clarke CL, Glanz JM, Xu S, Hambidge SJ, Donahue JG, Nordin JD, Klein NP, Jacobsen SJ, Naleway AL, Jackson ML, Lee G, Duffy J, Weintraub E. The safety of live attenuated influenza vaccine in children and adolescents 2 through 17 years of age: a Vaccine Safety Datalink study. Pharmacoepidemiol Drug Saf. 2018;27(1):59-68. doi: 10.1002/pds.4349. Epub 2017 Nov 17. PubMed

Stewart RJ, Flannery B, Chung JR, Gaglani M, Reis M, Zimmerman RK, Nowalk MP, Jackson L, Jackson ML. Influenza antiviral prescribing for outpatients with an acute respiratory illness and at high risk for influenza-associated complications during five influenza seasons, United States, 2011-2016. Clin Infect Dis. 2017 Oct 23. doi: 10.1093/cid/cix922. [Epub ahead of print]. PubMed



Flucasting week 15: Predicting influenza severity

The CDC warned in late January that this year's flu outbreak is more severe than any other since the 2009 swine flu pandemic, and that its intensity is still increasing. The evidence KPWHRI's Dr. Michael L. Jackson and team sees shows that influenza A(H1N1) and B are still increasing nationally, and that the A(H3N2) peak in Washington state seems to have passed.

Read it in News and Events.

KPWHRI In the Media

Flucasting: Predicting influenza severity

Are we prepared for the next flu pandemic?

U.S. News & World Report, Jan. 18, 2018

KPWHRI In the Media

Flucasting: Predicting influenza severity

Flu 2017: When the season will peak and when it will come to an end

Newsweek, Dec. 22, 2017

Live Healthy

Flu shots boost your chances of staying well

While flu vaccine effectiveness varies year to year, it still makes sense to get immunized annually.

Read about it in Live Healthy.