Jennifer McClure, PhD, is director of Investigative Science at Kaiser Permanente Washington Health Research Institute (KPWHRI). She is also a senior investigator and clinical psychologist whose research focuses on developing new interventions to reduce people’s risk of chronic disease and cancer or help them better manage existing chronic disease through:
Much of Dr. McClure’s research emphasizes creating highly individualized behavioral treatments that can be disseminated on a population level, through health care systems and tobacco quitlines or directly to individuals via digital health tools, such as mobile health (mHealth) apps. Her goal is to design programs that are effective, convenient, engaging, and cost-effective, understanding that to make the leap from research to real world, interventions should meet these criteria.
Dr. McClure is best known for her research creating novel treatments for nicotine dependence, particularly interventions targeted to smokers who are ambivalent about quitting. These individuals may want to quit smoking some day, but are not yet ready to give up tobacco. Most smokers fall into this category, but few interventions are targeted to this important group. Her research has demonstrated the effectiveness of using proactive counseling and online interventions to motivate and support smoking cessation among ambivalent smokers. Her work has also shed light on the potential risks and benefits of using biological indicators of disease or disease risk to motivate quitting. Now she is developing two new mHealth apps to help ambivalent smokers kick the habit: one designed for anyone who smokes and one designed specifically for smokers living with HIV.
Dr. McClure’s collaborative research covers a range of topics from reducing sedentary behavior to comparing the effectiveness of various strategies for assessing and diagnosing high blood pressure.
In recognition of her scientific contributions, Dr. McClure was named a fellow in the Society of Behavioral Medicine (SBM) in 2013 and a fellow in the Society for Research on Nicotine and Tobacco in 2018. In 2019 she joined the faculty of the Kaiser Permanente Bernard J Tyson School of Medicine as a professor in Health Systems Science. Dr. McClure is also an affiliate professor of health services at the University of Washington School of Public Health and an affiliate investigator in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center.
Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications; oral health promotion; dietary change; physical activity promotion; informed decision-making; psychoneuroimmunology; HIV
Development of eHealth and mHealth intervention tools
Depression treatment and development of behavior change interventions for people with serious mental illness
Prevention and treatment
Green BB, Anderson ML, Cook AJ, Ehrlich K, Hall YN, Hsu C, Joseph D, Klasnja P, Margolis KL, McClure JB, Munson SA, Thompson MJ. Clinic, home, and kiosk blood pressure measurements for diagnosing hypertension: a randomized diagnostic study. J Gen Intern Med. 2022 Mar 3. doi: 10.1007/s11606-022-07400-z. [Epub ahead of print]. PubMed
McClure JB, Catz SL, Chalal C, Ciuffetelli R, Coggeshall S, DeFaccio RJ, Fleehart S, Heffner JL, Thompson E, Williams EC, Crothers K. Design and methods of a randomized trial testing the novel Wellness Intervention for Smokers Living with HIV (WISH). Contemp Clin Trials. 2021;110:106486. doi: 10.1016/j.cct.2021.106486. Epub 2021 Oct 27. PubMed
Rosenberg DE, Greenwood-Hickman MA, Zhou J, Cook AJ, Mettert KD, Cooper J, Arterburn D, Green BB, Walsh-Bailey C, Kerr J, Owen N, Dunstan D, McClure JB. Protocol for a randomized controlled trial of sitting reduction to improve cardiometabolic health in older adults. Contemp Clin Trials. 2021 Dec;111:106593. doi: 10.1016/j.cct.2021.106593. Epub 2021 Oct 16. PubMed
Heffner JL, Watson NL, Dahne J, Croghan I, Kelly MM, McClure JB, Bars M, Thrul J, Meier E. Recognizing and preventing participant deception in online nicotine and tobacco research studies: suggested tactics and a call to action. Nicotine Tob Res. 2021 Apr 20:ntab077. doi: 10.1093/ntr/ntab077. Online ahead of print. PubMed
Schnoll R, Bernstein SL, Kaufman A, Gross R, Catz SL, Cioe PA, Hitsman B, Marhefka SL, Pacek LR, Vidrine DJ, Vilardaga R, Edelman EJ, McClure JB, Ashare R, Lockhart E, Crothers K. Covid-19 challenges confronted by smoking cessation clinical trials for people living with HIV: the experience of grantees of the United States National Cancer Institute. Nicotine Tob Res. 2021 Feb 28;ntab035. doi: 10.1093/ntr/ntab035. Online ahead of print. PubMed
Greenwood-Hickman MA, Dahlquist J, Cooper J, Holden E, McClure JB, Mettert KD, Perry SR, Rosenberg DE. "They're going to Zoom it": a qualitative investigation of impacts and coping strategies during the Covid-19 pandemic among older adults. Front Public Health. 2021 May 19;9:679976. doi: 10.3389/fpubh.2021.679976. eCollection 2021. PubMed
McClure JB, Lapham G. Tobacco quitline engagement and outcomes among primary care patients reporting use of tobacco or dual tobacco and cannabis: an observational study. Subst Abus. 2020 Dec 3:1-6. doi: 10.1080/08897077.2020.1846665. [Epub ahead of print]. PubMed
Heffner JL, Catz SL, Klasnja P, Tiffany B, McClure JB. Development of a mobile health intervention with personal experiments for smokers who are ambivalent about quitting: formative design and testing. JMIR Form Res. 2020;4(8):e21784. doi: 10.2196/21784. PubMed
Ashare RL, Bernstein SL, Schnoll R, Gross R, Catz SL, Cioe P, Crothers K, Hitsman B, Marhefka SL, McClure JB, Pacek LR, Vidrine DJ, Vilardaga R, Kaufman A, Edelman EJ. The United States National Cancer Institute’s coordinated research effort on tobacco use as a major cause of morbidity and mortality among people with HIV. Nicotine Tob Res. 2021 Jan 22;23(2):407-410. doi: 10.1093/ntr/ntaa155. PubMed
Rosenberg DE, Anderson ML, Renz A, Matson TE, Lee AK, Greenwood-Hickman MA, Arterburn DE, Gardiner PA, Kerr J, McClure JB. Reducing sitting time in obese older adults: the I-STAND randomized controlled trial. J Aging Phys Act. 2020 Jun 4:1-11. doi: 10.1123/japa.2019-0470. [Epub ahead of print]. PubMed
Research led by KPWHRI’s Beverly Green, MD, MPH, finds that patients prefer at-home monitoring of blood pressure.
Dr. Jennifer McClure shares advice and resources for staying physically and emotionally well during the COVID-19 crisis, and beyond.
As Dr. Jennifer McClure completes the last of three innovative studies, she reflects on how the work began, the difference it may make, and what happens next.
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.
Dr. Jennifer McClure applauds the American Cancer Society’s recent strike against tobacco that burns. And she unpacks its evidence-based stance on e-cigarettes.
Dr. Jennifer McClure reflects on using personalized genetic knowledge to improve health and health care.