Jennifer McClure, PhD, is a senior investigator and clinical psychologist whose research focuses on developing new interventions to reduce people’s risk of chronic disease and cancer or help them better manage existing chronic disease. Her work includes:
She also serves as Kaiser Permanente Washington Research Institute (KPWHRI)’s director of research, faculty, and development. In this role, Dr. McClure helps set the strategic vision for the institute, oversee policies and procedures relevant to the faculty, and ensure the institute’s financial growth and stability.
Much of Dr. McClure’s research emphasizes creating highly individualized behavioral treatments that can be disseminated on a population level, through health care systems and tobacco quitlines or directly to individuals via the internet and mobile health (mHealth) apps. Her goal is to design programs that are effective, convenient, engaging, and cost-effective, understanding that to make the leap from research to real world, interventions should meet these criteria.
Dr. McClure is best known for her research creating novel treatments for nicotine dependence, particularly interventions targeted to smokers who are ambivalent about quitting. These individuals may want to quit smoking eventually, but are not yet ready to give up tobacco. Most smokers fall into this category, but few interventions are targeted to this important group. Her research has demonstrated the effectiveness of using proactive counseling and online interventions to motivate and support smoking cessation among ambivalent smokers. Her work has also shed light on the potential risks and benefits of using biological indicators of disease or disease risk to motivate quitting. Now she is developing a new mHealth app to help ambivalent smokers kick the habit.
In other current work, Dr. McClure is examining smokers’ dual use of tobacco and marijuana—a growing public health problem as legalization of cannabis spreads. Her collaborative research covers a range of topics from reducing sedentary behavior to comparing the effectiveness of various strategies for assessing and diagnosing high blood pressure.
In recognition of her scientific contributions, Dr. McClure was named a fellow in the Society of Behavioral Medicine (SBM) in 2013 and a fellow in the Society for Research on Nicotine and Tobacco in 2018. Dr. McClure is an affiliate professor of health services at the University of Washington School of Public Health and an affiliate investigator in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. In 2008 she was named KPWHRI’s associate director of research. She assumed her role as director of research, faculty, and development in 2013.
Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications; oral health promotion; dietary change; physical activity promotion; and informed decision-making
Development of eHealth and mHealth intervention tools
Depression treatment and development of behavior change interventions for people with serious mental illness
Reid RJ, Anderson ML, Fishman PA, McClure JB, Johnson RL, Catz SL, Green BB. Relationship between cardiovascular risk and lipid testing in one health care system: a retrospective cohort study. BMC Health Serv Res. 2015 Jul 23;15:281. doi: 10.1186/s12913-015-0884-2. PubMed
Bergen AW, Michel M, Nishita D, Krasnow R, Javitz HS, Conneely KN, Lessov-Schlaggar CN, Hops H, Zhu AZ, Baurley JW, McClure JB, Hall SM, Baker TB, Conti DV, Benowitz NL, Lerman C, Tyndale RF, Swan GE. Drug metabolizing enzyme and transporter gene variation, nicotine metabolism, prospective abstinence, and cigarette consumption. PLoS One. 2015 Jul 1;10(7):e0126113. doi: 10.1371/journal.pone.0126113. eCollection 2015. PubMed
Eschler J, Kendall L, O'Leary K, Vizer LM, Lozano P, McClure JB, Pratt W, Ralston JD. Shared calendars for home health management. In Proceedings of the 18th ACM Conference on Computer Supported Cooperative Work & Social Computing (CSCW '15). 2015; ACM, New York, NY, USA, 1277-88. doi:10.1145/2675133.2675168.
Kendall L, Eschler J, Lozano P, McClure JB, Vizer LM, Ralston JD, Pratt W. Engineering for reliability in at-home chronic disease management. AMIA Annu Symp Proc. 2014 Nov 14;2014:777-86. eCollection 2014.
Bergen AW, Javitz HS, Krasnow R, Michel M, Nishita D, Conti DV, Edlund CK, Kwok PY, McClure JB, Kim RB, Hall S, Tyndale RF, Baker TB, Benowitz NL, Swan GE. Organic cation transporter variation and response to smoking cessation therapies. Nicotine Tob Res. 2014 Dec;16(12):1638-46. doi: 10.1093/ntr/ntu161. Epub 2014 Aug 20. PubMed
Cano MA, Lam CY, Chen M, Adams CE, Correa-Fernandez V, Stewart DW, McClure JB, Cinciripini PM, Wetter DW. Positive smoking outcome expectancies mediate the association between negative affect and smoking urge among women during a quit attempt. Exp Clin Psychopharmacol. 2014 Aug;22(4):332-40. doi: 10.1037/a0036749. Epub 2014 May 5. PubMed
Lam CY, Businelle MS, Aigner CJ, McClure JB, Cofta-Woerpel L, Cinciripini PM, Wetter DW. Individual and combined effects of multiple high-risk triggers on postcessation smoking urge and lapse. Nicotine Tob Res. 2014 May;16(5):569-75. doi: 10.1093/ntr/ntt190. Epub 2013 Dec 9. PubMed
McClure JB, Peterson D, Derry H, Riggs K, Saint-Johnson J, Nair V, An L, Shortreed SM. Exploring the "active ingredients" of an online smoking intervention: a randomized factorial trial. Nicotine Tob Res. 2014 Aug;16(8):1129-39. doi: 10.1093/ntr/ntu057. Epub 2014 Apr 11. PubMed
Green BB, Anderson ML, Cook AJ, Catz SL, Fishman PA, McClure JB, Reid RJ. E-care for heart wellness: a feasibility trial to decrease blood pressure and cardiovascular risk. Am J Prev Med. 2014;46(4):368-77. doi: 10.1016/j.amepre.2013.11.009. PubMed
Williams EC, Bradley KA, Balderson BH, McClure JB, Grothaus L, McCoy K, Rittmueller SE, Catz SL. Alcohol and associated characteristics among older persons living with HIV on antiretroviral therapy. Subst Abus. 2014;35(3):245-53. doi: 10.1080/08897077.2014.890997. PubMed
As Dr. Jennifer McClure completes the last of three innovative studies, she reflects on how the work began, the difference it may make, and what happens next.
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.
Dr. Jennifer McClure applauds the American Cancer Society’s recent strike against tobacco that burns. And she unpacks its evidence-based stance on e-cigarettes.
Dr. Jennifer McClure reflects on using personalized genetic knowledge to improve health and health care.
Dr. Jennifer McClure partnered with the leading quitline provider to see what happens when smokers are counseled about oral health and tobacco.