Jennifer F. Bobb, PhD

I am excited about the potential for scientific discovery in the era of big data. With critical scientific thinking and advanced statistical methods, we can leverage rich data sources to improve public health.

Jennifer F. Bobb, PhD

Assistant Investigator, Kaiser Permanente Washington Health Research Institute

Areas of focus:

Biography

Jennifer Bobb, PhD, aims to apply rigorous statistical methods to address important problems in public health. She is interested in statistical issues that occur when data that were not originally collected for research purposes, such as administrative claims data or electronic health records, are used for addressing scientific questions of relevance to clinical practice and health policy.

At KPWHRI, Dr. Bobb collaborates with scientists across a broad range of research areas, including studies of aging and cognitive function, women’s health, and behavioral health. As an investigator with the Addictions Research Network, she provides statistical leadership on pragmatic clinical trials at Kaiser Permanente Washington and other health systems. She is the lead statistician on a study to evaluate whether exposure to prescription opioids during early pregnancy increases the risk of neural tube defects, as part of the Medication Exposure in Pregnancy Risk Evaluation Program funded by the Food and Drug Administration (FDA), as well as on the Adult Changes in Thought (ACT) study, a cohort study investigating the factors that contribute to dementia, Alzheimer’s disease, and healthy aging.

Dr. Bobb also has expertise in environmental biostatistics, where she has led large-scale epidemiological investigations on the health effects of exposure to extreme heat and air pollution and worked with interdisciplinary teams to study the health impact of changing environmental stressors under global climate change. She also developed flexible modeling approaches for estimating the health effects of multi-pollutant mixtures that broadly apply to settings where a large number of exposures may interact or have complex relationships with health, along with publicly available software implementing these methods.

Dr. Bobb is an affiliate assistant professor in biostatistics at the University of Washington. She is also an associate editor of the journal Biostatistics. She serves on the Regional Advisory Board of the Western North American Region of the International Biometric Society and is a member of the American Statistical Association. Before joining KPWHRI, Dr. Bobb completed her PhD in biostatistics at the Johns Hopkins Bloomberg School of Public Health in 2012, followed by a postdoctoral fellowship at the Harvard T.H. Chan School of Public Health. 

Research interests and experience

  • Biostatistics

    Bayesian methods; analysis of observational data; hierarchical models; analysis of spatial-temporal data.

  • Environmental Health

    Health effects of air pollution, extreme weather events, climate change; statistical methods for complex environmental mixtures.

  • Women's Health

    Biostatistics; interventions during pregnancy; environmental exposures during pregnancy.

  • Mental Health

    Biostatistics; depression; dementia; behavioral health.

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Recent publications

Liu SH, Bobb JF, Claus Henn B, Gennings C, Schnaas L, Tellez-Rojo M, Bellinger D, Arora M, Wright RO, Coull BA. Bayesian varying coefficient kernel machine regression to assess neurodevelopmental trajectories associated with exposure to complex mixtures. Stat Med. 2018 Sep 12. doi: 10.1002/sim.7947. [Epub ahead of print]. PubMed

Glass JE, Bobb JF, Lee AK, Richards JE, Lapham GT, Ludman E, Achtmeyer C, Caldeiro RM, Parrish R, Williams EC, Lozano P, Bradley KA. Study protocol: a cluster-randomized trial implementing Sustained Patient-centered Alcohol-related Care (SPARC trial). Implement Sci. 2018;13(1):108. doi: 10.1186/s13012-018-0795-9. PubMed

Sordillo JE, Switkowski KM, Coull BA, Schwartz J, Kloog I, Gibson H, Litonjua AA, Bobb J, Koutrakis P, Rifas-Shiman SL, Oken E, Gold DR. Relation of prenatal air pollutant and nutritional exposures with biomarkers of allergic disease in adolescence. Sci Rep. 2018 Jul 12;8(1):10578. doi: 10.1038/s41598-018-28216-0. PubMed

Yitshak-Sade M, Bobb JF, Schwartz JD, Kloog I, Zanobetti A. The association between short and long-term exposure to PM2.5 and temperature and hospital admissions in New England and the synergistic effect of the short-term exposures. Sci Total Environ. 2018;639:868-875. doi: 10.1016/j.scitotenv.2018.05.181. Epub 2018 May 26. PubMed

Williams EC, McGinnis KA, Bobb JF, Rubinsky AD, Lapham GT, Skanderson M, Catz SL, Bensley KM, Richards JE, Bryant KJ, Edelman EJ, Satre DD, Marshall BDL, Kraemer KL, Blosnich JR, Crystal S, Gordon AJ, Fiellin DA, Justice AC, Bradley KA. Changes in alcohol use associated with changes in HIV disease severity over time: a national longitudinal study in the Veterans Aging Cohort. Drug Alcohol Depend. 2018 May 24;189:21-29. doi: 10.1016/j.drugalcdep.2018.04.022.[Epub ahead of print]. PubMed

Bradley KA, Bobb JF, Ludman EJ, Chavez LJ, Saxon AJ, Merrill JO, Williams EC, Hawkins EJ, Caldeiro RM, Achtmeyer CE, Greenberg DM, Lapham GT, Richards JE, Lee AK, Kivlahan DR. Alcohol-related nurse care management in primary care: a randomized clinical trial. JAMA Intern Med. 2018 Mar 26. pii: 2674869. doi: 10.1001/jamainternmed.2018.0388. [Epub ahead of print]. PubMed

 

KPWHRI IN THE MEDIA

Cardiovascular disease-related hospital admissions jump on second day after major snowfall

Heart hospitalizations may spike days after snowstorms pass

Reuters (syndicated), Jan. 30, 2017

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Mental health research excels at linking bad experiences to poor outcomes, writes Dr. Greg Simon. Here’s how to focus on recovery and resilience instead.

Read about it in Healthy Findings.

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Whether you try antidepressants, therapy, both, or neither, KPWHRI’s Dr. Gregory Simon points to 3 ‘active ingredients’ for feeling better.

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