Jennifer F. Bobb, PhD

I am excited about the potential for scientific discovery in the era of big data. With critical scientific thinking and advanced statistical methods, we can leverage rich data sources to improve public health.

Jennifer F. Bobb, PhD

Assistant Investigator, Kaiser Permanente Washington Health Research Institute

bobb.j@ghc.org
206-287-2190
Google Scholar
GitHub

Curriculum vitae (CV)

Areas of focus:

Biography

Jennifer Bobb, PhD, aims to apply rigorous statistical methods to address important problems in public health. She is interested in statistical issues that occur when data that were not originally collected for research purposes, such as administrative claims data or electronic health records, are used for addressing scientific questions of relevance to clinical practice and health policy.

At KPWHRI, Dr. Bobb collaborates with scientists across a broad range of research areas, including studies of aging and cognitive function, women’s health, and behavioral health. As an investigator with the Addictions Research Network, she provides statistical leadership on pragmatic clinical trials at Kaiser Permanente Washington and other health systems. She is the lead statistician on a study to evaluate whether exposure to prescription opioids during early pregnancy increases the risk of neural tube defects, as part of the Medication Exposure in Pregnancy Risk Evaluation Program funded by the Food and Drug Administration (FDA), as well as on the Adult Changes in Thought (ACT) study, a cohort study investigating the factors that contribute to dementia, Alzheimer’s disease, and healthy aging.

Dr. Bobb also has expertise in environmental biostatistics, where she has led large-scale epidemiological investigations on the health effects of exposure to extreme heat and air pollution and worked with interdisciplinary teams to study the health impact of changing environmental stressors under global climate change. She also developed flexible modeling approaches for estimating the health effects of multi-pollutant mixtures that broadly apply to settings where a large number of exposures may interact or have complex relationships with health, along with publicly available software implementing these methods.

Dr. Bobb is an affiliate assistant professor in biostatistics at the University of Washington. She is also an associate editor of the journal Biostatistics. She serves on the Regional Advisory Board of the Western North American Region of the International Biometric Society and is a member of the American Statistical Association. Before joining KPWHRI, Dr. Bobb completed her PhD in biostatistics at the Johns Hopkins Bloomberg School of Public Health in 2012, followed by a postdoctoral fellowship at the Harvard T.H. Chan School of Public Health. 

Research interests and experience

  • Biostatistics

    Bayesian methods; analysis of observational data; hierarchical models; analysis of spatial-temporal data.

  • Environmental Health

    Health effects of air pollution, extreme weather events, climate change; statistical methods for complex environmental mixtures.

  • Women's Health

    Biostatistics; interventions during pregnancy; environmental exposures during pregnancy.

  • Mental Health

    Biostatistics; depression; dementia; behavioral health.

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Recent publications

Bobb JF, Lee AK, Lapham GT, Oliver M, Ludman E, Achtmeyer C, Parrish R, Caldeiro RM, Lozano P, Richards JE, Bradley KA. Evaluation of a pilot implementation to integrate alcohol-related care within primary care. Int J Environ Res Public Health. 2017 Sep 8;14(9). pii: E1030. doi: 10.3390/ijerph14091030. PubMed

Liu SH, Bobb JF, Lee KH, Gennings C, Henn BC, Bellinger D, Austin C, Schnaas L, Tellez-Rojo MM, Hu H, Wright RO, Arora M, Coull BA. Lagged kernel machine regression for identifying time windows of susceptibility to exposures of complex mixtures. Biostatistics. 2017 Sep 6. doi: 10.1093/biostatistics/kxx036. [Epub ahead of print]. PubMed

Valeri L, Mazumdar MM, Bobb JF, Claus Henn B, Rodrigues E, Sharif OIA, Kile ML, Quamruzzaman Q, Afroz S, Golam M, Amarasiriwardena C, Bellinger DC, Christiani DC, Coull BA, Wright RO. The joint effect of prenatal exposure to metal mixtures on neurodevelopmental outcomes at 20-40 months of age: evidence from rural Bangladesh. Environ Health Perspect. 2017 Jun 26;125(6):067015. doi: 10.1289/EHP614. PubMed

Bradley KA, Ludman EJ, Chavez LJ, Bobb JF, Ruedebusch SJ, Achtmeyer CE, Merrill JO, Saxon AJ, Caldeiro RM, Greenberg DM, Lee AK, Richards JE, Thomas RM, Matson TE, Williams EC, Hawkins E, Lapham G, Kivlahan DR. Patient-centered primary care for adults at high risk for AUDs: the Choosing Healthier Drinking Options In primary CarE (CHOICE) trial. Addict Sci Clin Pract. 2017 May 17;12(1):15. doi: 10.1186/s13722-017-0080-2. PubMed

Williams EC, Lapham GT, Bobb JF, Rubinsky AD, Catz SL, Shortreed SM, Bensley KM, Bradley KA. Documented brief intervention not associated with resolution of unhealthy alcohol use one year later among VA patients living with HIV. J Subst Abuse Treat. 2017 Jul;78:8-14. doi: 10.1016/j.jsat.2017.04.006. Epub 2017 Apr 13. PubMed

Williams EC, Lapham GT, Shortreed SM, Rubinsky AD, Bobb JF, Bensley KM, Catz SL, Richards JE, Bradley KA. Among patients with unhealthy alcohol use, those with HIV are less likely than those without to receive evidence-based alcohol-related care: a national VA study. Drug Alcohol Depend. 2017 May 1;174:113-120. doi: 10.1016/j.drugalcdep.2017.01.018. Epub 2017 Mar 6. PubMed

 

KPWHRI IN THE MEDIA

Cardiovascular disease-related hospital admissions jump on second day after major snowfall

Heart hospitalizations may spike days after snowstorms pass

Reuters (syndicated), Jan. 30, 2017

precision medicine

Can precision medicine break the chain of mental health co-misery?

Mental health research excels at linking bad experiences to poor outcomes, writes Dr. Greg Simon. Here’s how to focus on recovery and resilience instead.

Read about it in Healthy Findings.

Live Healthy

What’s the best treatment for depression?

Whether you try antidepressants, therapy, both, or neither, KPWHRI’s Dr. Gregory Simon points to 3 ‘active ingredients’ for feeling better.

Read about it in Live Healthy.