Preventive Medicine

“We want to help people stay healthy and prevent illness, so we’re seeking the best evidence and testing innovative new ways to make screening and health promotion part of everyday clinical practice.”

Nora Henrikson, PhD, MPH
Assistant Investigator, Kaiser Permanente Washington Health Research Institute

Research overview

Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping illness or injury from happening. Yet that’s the goal of research on preventive care.

Most Kaiser Permanente Washington scientists study prevention, whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.

Examples include research in areas such as:

Evidence-based practice reviews

A team of researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) produces reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. We do this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 13 centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.

Immunization

We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, to improve their uptake.

Drug safety

We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.

Screening

Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.

Health promotion

Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.

Recent publications on Addictions

Glass JE, Dorsey CN, Beatty T, Bobb JF, Wong ES, Palazzo L, King D, Mogk J, Stefanik-Guizlo K, Idu A, Key D, Fortney JC, Thomas R, McWethy AG, Caldeiro RM, Bradley KA Study protocol for a factorial-randomized controlled trial evaluating the implementation, costs, effectiveness, and sustainment of digital therapeutics for substance use disorder in primary care (DIGITS Trial) 2023 Feb;18(1):3. doi: 10.1186/s13012-022-01258-9. Epub 2023-02-01. PubMed

Luderer H, Enman N, Gerwien R, Braun S, McStocker S, Xiong X, Koebele C, Cannon C, Glass J, Maricich Y A Prescription Digital Therapeutic to Support Unsupervised Buprenorphine Initiation for Patients With Opioid Use Disorder: Protocol for a Proof-of-Concept Study 2023 Jan 20;12:e43122. doi: 10.2196/43122. Epub 2023-01-20. PubMed

Scherrer JF, Salas J, Grucza R, Wilens T, Quinn PD, Sullivan MD, Rossom RC, Wright E, Piper B, Sanchez K, Lapham G Prescription stimulant use during long-term opioid therapy and risk for opioid use disorder 2022 Dec;5:100122. doi: 10.1016/j.dadr.2022.100122. Epub 2022-11-24. PubMed

Matson TE, Harris AHS, Chen JA, Edmonds AT, Frost MC, Rubinsky AD, Blosnich JR, Williams EC Influence of a national transgender health care directive on receipt of alcohol-related care among transgender Veteran Health Administration patients with unhealthy alcohol use 2022 Dec;143:108808. doi: 10.1016/j.jsat.2022.108808. Epub 2022-05-24. PubMed

Braciszewski JM, Idu AE, Yarborough BJH, Stumbo SP, Bobb JF, Bradley KA, Rossom RC, Murphy MT, Binswanger IA, Campbell CI, Glass JE, Matson TE, Lapham GT, Loree AM, Barbosa-Leiker C, Hatch MA, Tsui JI, Arnsten JH, Stotts A, Horigian V, Hutcheson R, Bart G, Saxon AJ, Thakral M, Ling Grant D, Pflugeisen CM, Usaga I, Madziwa LT, Silva A, Boudreau DM Sex Differences in Comorbid Mental and Substance Use Disorders Among Primary Care Patients With Opioid Use Disorder 2022 Dec;73(12):1330-1337. doi: 10.1176/appi.ps.202100665. Epub 2022-06-16. PubMed

Researchers in Addictions

Julie Angerhofer, PhD, MPH

Associate Investigator
206-287-2100
Julie.E.Angerhofer@kp.org

Curriculum vitae (CV)

Jennifer F. Bobb, PhD

Senior Biostatistics Investigator
206-287-2190
Jennifer.F.Bobb@kp.org

Curriculum vitae (CV)

Katharine A. Bradley, MD, MPH

Senior Investigator
206-287-2151
Katharine.A.Bradley@kp.org

Curriculum vitae (CV)

Clarissa Hsu, PhD

Associate Investigator
206-287-4276
Clarissa.W.Hsu@kp.org

Curriculum vitae (CV)

Noorie Hyun, PhD

Associate Biostatistics Investigator
Noorie.Hyun@kp.org

Curriculum vitae (CV)

Morgan Justice, PhD, MA

Senior Collaborative Scientist
Morgan.J.Fuoco@kp.org

Curriculum vitae (CV)

Gwen Lapham, PhD, MPH, MSW

Associate Investigator
206-287-2021
Gwen.T.Lapham@kp.org

Curriculum vitae (CV)

Theresa E. Matson, PhD, MPH

Collaborative Scientist
Tessa.E.Matson@kp.org

Curriculum vitae (CV)

Jess Mogk, MPH

Collaborative Scientist
Jessica.M.Mogk@kp.org

Curriculum vitae (CV)

Yu-Ru Su, PhD

Associate Biostatistics Investigator
206-287-2948
YuRu.Su@kp.org

Curriculum vitae (CV)

Paige D. Wartko, PhD, MPH

Senior Collaborative Scientist
206-442-5230
Paige.D.Wartko@kp.org

Curriculum vitae (CV)