Preventive Medicine

“We want to help people stay healthy and prevent illness, so we’re seeking the best evidence and testing innovative new ways to make screening and health promotion part of everyday clinical practice.”

Nora Henrikson, PhD, MPH
Assistant Investigator, Kaiser Permanente Washington Health Research Institute

Research overview

Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping illness or injury from happening. Yet that’s the goal of research on preventive care.

Most Kaiser Permanente Washington scientists study prevention, whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.

Examples include research in areas such as:

Evidence-based practice reviews

A team of researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) produces reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. We do this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 13 centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.

Immunization

We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, to improve their uptake.

Drug safety

We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.

Screening

Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.

Health promotion

Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.

Recent publications on Addictions

Frost MC, Blosnich JR, Lehavot K, Chen JA, Rubinsky AD, Glass JE, Williams EC Disparities in Documented Drug Use Disorders Between Transgender and Cisgender U.S. Veterans Health Administration Patients 2021 Jul;15(4):334-340. doi: 10.1097/ADM.0000000000000769. PubMed

Simon CB, Klein JW, Bradley KA, Oliver M Primary Care Patients with Opioid Use Disorder Have a High Prevalence of Pain and Mental Health and Other Substance Use Disorders 2021 Jun;36(6):1799-1801. doi: 10.1007/s11606-020-05820-3. Epub 2020-05-29. PubMed

Firemark AJ, Schneider JL, Kuntz JL, Papajorgji-Taylor D, Dickerson JF, Thorsness LA, Reese KR, Sullivan MD, Debar LL, Smith DH "We Need to Taper." Interviews with Clinicians and Pharmacists About Use of a Pharmacy-Led Opioid Tapering Program 2021 May 21;22(5):1213-1222. doi: 10.1093/pm/pnaa442. PubMed

Matson TE, Carrell DS, Bobb JF, Cronkite DJ, Oliver MM, Luce C, Ghitza UE, Hsu CW, Campbell CI, Browne KC, Binswanger IA, Saxon AJ, Bradley KA, Lapham GT Prevalence of Medical Cannabis Use and Associated Health Conditions Documented in Electronic Health Records Among Primary Care Patients in Washington State 2021 May 3;4(5):e219375. doi: 10.1001/jamanetworkopen.2021.9375. Epub 2021-05-03. PubMed

Hser YI, Ober AJ, Dopp AR, Lin C, Osterhage KP, Clingan SE, Mooney LJ, Curtis ME, Marsch LA, McLeman B, Hichborn E, Lester LS, Baldwin LM, Liu Y, Jacobs P, Saxon AJ. Is telemedicine the answer to rural expansion of medication treatment for opioid use disorder? early experiences in the feasibility study phase of a national drug abuse treatment clinical trials network trial.  Addict Sci Clin Pract. 2021;16(1):24. doi: 10.1186/s13722-021-00233-x.  PubMed

Researchers in Addictions

Julie Angerhofer, PhD, MPH

Associate Investigator
206-287-2100
Julie.E.Angerhofer@kp.org

Curriculum vitae (CV)

Jennifer F. Bobb, PhD

Senior Biostatistics Investigator
206-287-2190
Jennifer.F.Bobb@kp.org

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Katharine A. Bradley, MD, MPH

Senior Investigator
206-287-2151
Katharine.A.Bradley@kp.org

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Clarissa Hsu, PhD

Associate Investigator
206-287-4276
Clarissa.W.Hsu@kp.org

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Noorie Hyun, PhD

Associate Biostatistics Investigator
Noorie.Hyun@kp.org

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Morgan Justice, PhD, MA

Senior Collaborative Scientist
Morgan.J.Fuoco@kp.org

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Gwen Lapham, PhD, MPH, MSW

Associate Investigator
206-287-2021
Gwen.T.Lapham@kp.org

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Theresa E. Matson, PhD, MPH

Collaborative Scientist
Tessa.E.Matson@kp.org

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Jess Mogk, MPH

Collaborative Scientist
Jessica.M.Mogk@kp.org

Curriculum vitae (CV)

Yu-Ru Su, PhD

Associate Biostatistics Investigator
206-287-2948
YuRu.Su@kp.org

Curriculum vitae (CV)

Paige D. Wartko, PhD, MPH

Senior Collaborative Scientist
206-442-5230
Paige.D.Wartko@kp.org

Curriculum vitae (CV)