Grants Awarded


January 2018

KPWHRI recently received word of 18 new awards.

3rd Seattle Symposium on Health Care Data Analytics

A one-year, $14,000 grant from KPWHRI Development Fund. Major goals: To strengthen collaborative relationships between field-leading biostatisticians and other scientists in health care analytics, to possibly publish a supplement in a special issue of a statistical or analytics journal, and to strengthen our national reputation as a leader in methods for health care data analytics. The principal investigator is Jennifer C. Nelson.

 

A Reusable, Generalizable Method to Link Health Plan Claims Data with the National Death Index Plus to Examine the Association Between Medical Products and Death and Causes of Death

A one-year, $152,149 grant from Food and Drug Administration. Major goals: To develop a reusable, generalizable method of linking multiple health plan databases with the Centers for Disease Control and Prevention’s National Death Index Plus (NDI+) data. This will be done using the distributed data network and infrastructure of the Food and Drug Administration (FDA)’s Sentinel System. The project will focus on FDA’s need to conduct population-based, post-market assessments of death and specific causes of death as outcomes in both safety and effectiveness analyses. We will pilot the feasibility of the developed approach through a use case designed to examine the associations between select antidepressants and all-cause mortality and specific causes of death (e.g., cardiovascular death). The Kaiser Permanente Washington Health Research Institute lead investigator is Denise M. Boudreau.

 

Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE)

A three-year, $100,000 grant from Patient-Centered Outcomes Research Institute. Major goals: ADAPTABLE is a large pragmatic trial comparing low- and moderate-dose aspirin for prevention of cardiovascular events. Kaiser Permanente Washington Health Research Institute (KPWHRI) will collaborate in the independent evaluation of the ADAPTABLE trial, specifically focused on recruitment strategies, outcome ascertainment, stakeholder engagement, and governance. The Kaiser Permanente Washington Health Research Institute lead investigator is Gregory E. Simon.

 

BP-CHECK Comparative Cost Effectiveness and Automated Office Blood Pressure (BP) Measurements Pilot

A one-year, $55,988 grant from KPWHRI Development Fund. Major goals: To determine the difference between automated office Blood Pressure (BP) measurements (average of 3 measurements) compared to 24-hour ambulatory BP monitoring and to determine whether being alone in a room or having the examiner in the room makes a difference on automated office BP measurements. The principal investigator is Beverly B. Green.

 

CCALAC (Community Clinic Association of Los Angeles County) -AFS (Advancing the Financial Strength of LA Clinics Project)

A one-year, $50,000 grant from Cedars-Sinai. Major goals: TBD. The Kaiser Permanente Washington Health Research Institute lead investigator is Lisa Schafer.

 

Expanding the (My Mobile Advice Program) MyMAP Mobile Health (mHealth) Intervention for Smoking Cessation

A one-year, $65,068 grant from KPWHRI Development Fund. Major goals: To expand and update the MyMAP (My Mobile Advice Program) for use with additional pharmacotherapies and patient populations. The principal investigator is Jennifer B. McClure.

 

Honoring What Matters to Patients with Multiple Chronic Conditions - Feasibility Study

A one-year, $107,409 grant from KPWHRI Development Fund. Major goals: To engage patients, family caregivers and primary and palliative care providers to establish specifications for integrating the personal values into primary care via a values-elicitation tool and clinical workflows; and test the feasibility and acceptability of using the tool and workflows for eliciting and using personal values to guide care in a pilot study of patients with multiple chronic conditions in primary care. The principal investigator is James D. Ralston.

 

Human Papillomavirus (HPV) Boost Pilot (FHCRC)

A six-month, $10,036 grant from Fred Hutchinson Cancer Research Center. Major goals: To assess the willingness of Kaiser Permanente Washington patients ages 9 to 19 years old who have received only a single dose of HPV vaccine to participate in a larger study of an HPV booster vaccine. The results of this pilot will inform study feasibility and recruitment strategies for a February 2018 grant application to National Institute of Allergy and Infectious Diseases (NIAID) which will seek to provide data to inform future HPV vaccine dosing schedules, including whether a reduced, two-dose series is sufficient for individuals aged 15-26 years. The principal investigator is Aruna Kamineni.

 

Impact of Medicare Transitions in the Washington (WA)-All Payer Claims Dataset

A one-year, $99,993 grant from KPWHRI Development Fund. Major goals: To target the gaps in our understanding about the benefits and harms of Medicare transitions by implementing methods to characterize the direction and magnitude of changes in medical and pharmacy benefits and provider networks that occur as a result of Medicare eligibility. The principal investigator is Kai Yeung.

 

Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Functioning, and Quality of Life in Veterans

A two-year, $17,114 grant from National Center for Complementary and Integrative Health. Major goals: To implement a new Whole Health model for chronic pain care emphasizing nondrug pain self-management that reduces pain symptoms and improves overall functioning and quality of life in veterans. This pragmatic trial will enroll over 600 veterans with moderate to severe chronic pain across multiple Veteran Affairs (VA) health care centers. The Kaiser Permanente Washington Health Research Institute lead investigator is Lynn DeBar.

 

Improving Identification of Suicide Risk via Routine Screening for Depression and Alcohol Use

A six-month, $40,048 grant from KPWHRI Development Fund. Major goals: To evaluate the association between alcohol use and suicide attempt (non-fatal and deaths); and to evaluate how different patterns of alcohol use influence the relationship between suicidal ideation and suicide attempt. This work will support development of the analytic methods to determine whether population-based alcohol and depression screening information, increasingly obtained in health systems across the U.S., can be used to better identify patients who will attempt and may die by suicide. The principal investigator is Julie E. Richards.

 

Learning Health Systems Mentored Career Development Program (K12)

A four-month, $21,723 grant from KPWHRI Development Fund. Major goals: To build a Learning Health Systems Mentored Career Development Program in collaboration with colleagues at University of Washington, Veteran’s Affairs Health Services Research and Development Service, and Washington State University. The principal investigator is Diana S. Buist.

 

Methods for Tracking Intervention Adaptation and Implementation Strategies - Part 2

A one-year, $120,008 grant from KPWHRI Development Fund. Major goals: To obtain pilot data to support an R01 application that would develop pragmatic measures and methods for tracking tailoring of implementation strategies and treatment adaptation in the context of a depression prevention implementation trial. The principal investigator is Cara C. Lewis. (R217176001)

 

(Mobile Health) mHealth in Interventions to Augment Medication Treatment of Opioid Use Disorder in Primary Care

A one-year, $83,755 grant from KPWHRI Development Fund. Major goals: To pilot the feasibility of using mHealth platforms to augment buprenorphine treatment in primary care. The principal investigator is Joseph E. Glass.

 

Project Connect

A one-year, $65,583 grant from KPWHRI Development Fund. Major goals: To understand KPWA member and clinician experiences with peer support and other systems as young patients (aged 25-45) with complex medical conditions and caregivers of young patients through survey and qualitative interviews. The principal investigator is Karen Wernli.

 

Tapering Off Opioids-Grant Proposal Development Funds

A six-month, $43,045 grant from KPWHRI Development Fund. Major goals: TBD. The principal investigator is Clarissa Hsu.

 

The California Endowment (TCE)- California Leadership Academy for the Public's Health (CaLAPH) Cohort 4

A one-year, $5,000 grant from The California Endowment. Major goals: To evaluate the 2018 cohort of the California Leadership Academy for the Public's Health (CaLAPH). The Kaiser Permanente Washington Health Research Institute lead investigator is Maggie Jones.

 

User-Centered Design of Tools for Explaining Chronic Back Pain to Patients

A six-month, $31,670 grant from KPWHRI Development Fund. Major goals: To develop a tool that can guide primary care clinicians in explaining chronic back pain and its self-management to patients. The principal investigator is Michael R. Von Korff.