Grants Awarded



April 2017

KPWHRI recently received word of four new awards.

A Big Data Research Study on the Relationship Between Metformin Use and Dementia

A two-year, $158,304 grant from National Institute on Aging. Major goals: To examine whether metformin use is associated with lower risk of incident dementia in people with diabetes mellitus, including: 1) to determine whether people who initiate treatment with metformin have a lower risk of dementia than people initiating treatment with a sulfonylurea; 2) to determine whether people who initiate treatment with metformin are at lower risk than comparable people who delay pharmacologic treatment; and 3) to explore whether the association between metformin and dementia differs by age or gender. The KPWHRI lead investigator is Sascha Dublin.

 

Center for Care Innovations Kaiser Permanente (KP) Transformation Accelerator

A two-year, $121,563 grant from Kaiser Foundation Health Plan. Major goals: To conduct the evaluation of the Transformation Accelerator program, including contributions to capacity development, effectiveness of the model, and spread to other Kaiser Permanente regions. The KPWHRI lead investigator is Maggie Jones.

 

Methods for Tracking Intervention Adaptation and Implementation Strategies

A nine-month, $20,005 grant from KPWHRI Development Fund. Major goals: To obtain pilot data to support an R01 application that would develop pragmatic measures and methods for tracking tailoring of implementation strategies and treatment adaptation in the context of a depression prevention implementation trial. The principal investigator is Cara C. Lewis.

 

Population-Based Incidence of Respiratory Syncytial Virus Across Multiple Years in the US (Code: RSV00022)

A one-year, $563,247 grant from Sanofi Pasteur. Major goals: Using specimens collected as part of the US Flu Vaccine Effectiveness study, we will estimate the incidence of medically attended Respiratory Syncytial Virus (RSV) in the Kaiser Permanente Washington population. For this, the University of Washington clinical virology lab will test stored specimens for RSV, and we will use the test results to calculate cumulative incidence of RSV by age group and year. The principal investigator is Michael L. Jackson.


March 2017

KPWHRI recently received word of six new awards.

Comorbidity and Screening Outcomes Among Older Women Undergoing Mammography

A four-year, $807,815 grant from National Cancer Institute. Major goals: To conduct analyses to optimize or enhance screening by considering advances in cancer control in two areas: polygenic genetic risk and emerging screening technologies. Both of these are linked to risk of developing a particular molecular sub-type of tumor based on Estrogen Receptor/Human Epidermal Growth Factor Receptor 2 (ER/HER2). The modeling groups will also research the outcomes of watchful waiting approaches for screen-detected Ductal carcinoma in situ (DCIS) and evaluate molecular-targeted treatments for invasive cancers. The Kaiser Permanente of Washington Health Research Institute lead investigator is Diana S. Buist.

 

Center of Youth Wellness (CYW)-Evaluation of National Pediatric Practice Community (NPPC) on Adverse Childhood Experiences (ACEs) Screening

A ten-month, $61,454 grant from Center for Youth Wellness. Major goals: To conduct an evaluation of a national practice community of pediatric providers to assess if and how their awareness, knowledge, and behaviors have changed related to screening kids for Adverse Childhood Experiences (ACEs) and providing appropriate follow up. We will also perform a retrospective analysis of two years of clinical data to see what (if any) effect ACEs screening and intervention has had on pediatric health outcomes. The principal investigator is Lisa Schafer.

 

Data Infrastructure for Feedback-Informed Care

A one-year, $265,553 grant from Garfield Memorial Foundation. Major goals: To implement improvements to existing virtual data warehouse (VDW) tables to support timely reporting of depression outcomes, develop analytic methods for personalized outcome predictions, design reporting tools for providers and patients. The Kaiser Permanente of Washington Health Research Institute lead investigator is Gregory E. Simon.

 

Montana Healthcare Foundation - Perinatal Drug Use Program Evaluation

A five-month, $17,150 grant from Montana Healthcare Foundation. Major goals: To work with Community Health Partners to evaluate a program addressing perinatal drug use. The principal investigator is Lorella Palazzo.

 

Risk of Hospitalization Following Chemotherapy - a Validation Study

A four-month, $17,600 grant from American Society of Clinical Oncology. Major goals: To validate a program already developed at two other Cancer Research Network sites. The Kaiser Permanente of Washington Health Research Institute lead investigator is Erin J. Bowles.

 

The Effectiveness, Safety, and Costs of Guideline-Concordant Lung Nodule Care

A four-year, $557,594 grant from National Cancer Institute. Major goals: To guide efforts to improve care and outcomes for 1.5 million people diagnosed with a lung nodule each year. We will evaluate the risks, benefits and costs of individuals receiving varying diagnostic intensities for incidentally detected lung nodules. The Kaiser Permanente of Washington Health Research Institute lead investigator is Diana S. Buist.

 


February 2017

KPWHRI recently received word of four new awards.

Advancing Implementation Science through Measure Development and Evaluation - Diversity Supplement

A two-year, $86,469 grant from National Institute of Mental Health. Major goals: To develop psychometrically strong and pragmatic measures and methods for implementation science. The principal investigator is Cara C. Lewis. (R216073030)

 

Cowlitz School Gardens

A one-year, $17,000 grant from Kaiser Foundation Health Plan. Major goals: To evaluate the impact of a school garden curriculum on youth food related attitudes and behavior. The principal investigator is Diana Charbonneau. (R216144001)

 

Population-Based Research Optimizing Screening Through Personalized Regimens (PROSPR): Studying Colorectal Cancer Effectiveness of Screening Strategies (SuCCESS) and Cervical Cancer Unit (CCU) Bridge Funding

A seven-month, $660,481 grant from National Cancer Institute. Major goals: To complete, during a close-out period, activities associated with PROSPR: Studying Colorectal Cancer Effectiveness of Screening Strategies (SuCCESS) and the Cervical Cancer Unit. The principal investigators are Jessica Chubak and Aruna Kamineni. (R210174050)

 

Washington (WA) State Insurance Exchange Enrollee Analysis

A one-year, $12,322 grant from Group Health Research Institute Directors Project Resource Fund. Major goals: To characterize and compare the demographic characteristics and utilization patterns of people who sign up through various types of insurance available in the individual and family health insurance market, individual coverage through the Washington State Health Benefits Exchange, individual coverage directly, and employer sponsored insurance/commercial. The principal investigator is David C. Grossman. (R216119001)


January 2017

GHRI recently received word of 19 new awards.

A Pilot Study of the Social Determinants of Healthcare for Substance Use Disorders

A one-year, $70,000 grant from Group Health Research Institute Development Fund. Major goals: To describe racial/ethnic, gender, and economic differences in the receipt of services for substance use disorders and demonstrate the feasibility of using Group Health medical charts to identify differences between these groups in how clinicians establish a diagnosis of substance use disorder. The principal investigator is Joseph E. Glass.

 

BP-CHECK Automated Office Blood Pressure (BP) Measurements

A nine-month, $30,235 grant from Group Health Research Institute Development Fund. Major goals: To add a fourth method of diagnosing hypertension, automated office blood pressure monitoring, to an existing study comparing multiple methods of diagnosing hypertension. The principal investigator is Beverly B. Green.

 

Building a Cost Effectiveness Analysis and Modeling Resource for Group Health Research Institute (GHRI)

A one-year, $50,000 grant from Group Health Research Institute Development Fund. Major goals: To develop a resource that would strength analytic and methodological capacity in cost-effectiveness analysis. The principal investigator is Kai Yeung.

 

Cancer Survivor Survey on Electronic Cigarettes and Symptom Burden

A six-month, $35,846 grant from Group Health Research Institute Development Fund. Major goals: To describe e-cigarette use and beliefs among lung and head and neck cancer survivors and estimate the prevalence of general and disease-specific symptoms in lung and head and neck cancer survivors. The principal investigator is Jessica Chubak.

 

Cannabis Use During Pregnancy:  Pilot Quantitative and Qualitative Data Needed to Obtain National Institute on Drug Abuse (NIDA) Funding

A one-year, $69,518 grant from Group Health Research Institute Development Fund. Major goals: To conduct preliminary quantitative and qualitative pilot work to describe the prevalence of cannabis use and the pregnancy outcomes, as well as possible reasons for cannabis use, among pregnant women attending Group Health in preparation for a future National Institute on Drug Abuse (NIDA) funded grant. The principal investigator is Gwen Lapham.

 

Center for Care Innovations - Safety Net Analytics Program

A one-year, $74,600 grant from Cedars-Sinai. Major goals: To evaluate the effectiveness of CCI's Safety Net Analytics Program to elevate successes and identify areas for improvement and spread. The Group Health Research Institute lead investigator is Maggie Jones.

 

Clare Fertility 2017

A one-year, $67,377 grant from Group Health Research Institute Development Fund. Major goals: To understand the lived experiences of adolescent and young adult (AYA) patients with advanced cancer who are making decisions about fertility preservation and family planning, and to use this understanding to make recommendations to care professionals who are advising AYA patients as they make choices about treatment. The principal investigator is Marlaine Gray.

 

Clare Opioids

A one-year, $30,375 grant from Group Health Research Institute Development Fund. Major goals: To understand the use of opioids in national claims based data for adolescent and young adult (AYA) patients. The principal investigator is Karen Wernli.

 

Developing Expertise in the Processing and Analysis of Accelerometer Data

A one-year, $40,000 grant from Group Health Research Institute Development Fund. Major goals: To develop biostatistical expertise at Group Health Research Institute (GHRI) for the analysis of accelerometer data. The newly developed expertise we be applied to advance two currently funded GHRI projects led by Dr. Rosenberg (ACT and ISTAND), and will provide the biostatistical knowledge base that will enable these data to be used successfully in future grant applications for ACT specifically and for the broader research institute. The principal investigator is Dori E. Rosenberg.

 

Development and Validation of a Tool for Automated Monitoring of Medication Allergies and Side Effects (AMMASE)

A six-month, $37,256 grant from Group Health Research Institute Development Fund. Major goals: To develop a natural language processing (NLP) system to automate the capture of medication side effect (MSE) descriptions appearing in electronic clinical text. This NLP system will be used to investigate the impact of MSEs on treatment adherence and outcomes for Group Health patients receiving antidepressants and antipsychotic medications.  The project will also support preparation of an external grant proposal. The principal investigator is David S. Carrell.

 

Group Health Cancer Research Program Research Specialist Award

A five-year, $948,128 grant from National Cancer Institute. Major goals: To support Erin Bowles as a scientist in various GHRI cancer research programs. The principal investigator is Erin J. Bowles.

 

Opening the Notes of Specialty Electronic Consultations to Patients

A one-year, $69,918 grant from Group Health Research Institute Development Fund. Major goals: To describe the initial experiences of patients, primary care providers, and specialty consultants with sharing electronic consultations with patients online and describe the initial adoption and use of shared electronic consultation with patients on line. The principal investigator is James D. Ralston.

 

Patient Perspectives on Routine Suicidality Screening: A Qualitative Evaluation

A one-year, $40,001 grant from Group Health Research Institute Development Fund. Major goals: To leverage behavioral health integration in the Group Health delivery system and examine the patient experience of being assessed for suicidality in the context of routine care. The principal investigator is Julie E. Richards.

 

Public Health Institute (PHI)-National Leadership Academy for the Public’s Health (NLAPH) Cohort 6 (C6) Appalachia

A ten-month, $5,000 grant from Centers for Disease Control and Prevention. Major goals: To evaluate the effectiveness of this leadership development program and provide information to Public Health Institute to inform course corrections. The Group Health Research Institute lead investigator is Maggie Jones.

 

Public Health Institute (PHI)-National Leadership Academy for the Public’s Health (NLAPH) Cohort 6 (C6) Competitive

A ten-month, $5,000 grant from Centers for Disease Control and Prevention. Major goals: To evaluate the effectiveness of this leadership development program and provide information to Public Health Institute to inform course corrections. The Group Health Research Institute lead investigator is Maggie Jones.

 

Public Health Institute (PHI)-National Leadership Academy for the Public’s Health (NLAPH) Cohort 6 (C6) US Virgin Islands (USVI)

A ten-month, $5,500 grant from Centers for Disease Control and Prevention. Major goals: To evaluate the effectiveness of this leadership development program and provide information to Public Health Institute to inform course corrections. The Group Health Research Institute lead investigator is Maggie Jones.

 

Public Health Institute (PHI)-National Leadership Academy for the Public’s Health (NLAPH) Cohort 6 (C6) Zika

A ten-month, $10,000 grant from Centers for Disease Control and Prevention. Major goals: To evaluate the effectiveness of this leadership development program and provide information to Public Health Institute to inform course corrections. The Group Health Research Institute lead investigator is Maggie Jones.

 

Physician Coaching: Value-Based Referrals

A one-year, $70,088 grant from Group Health Research Institute Development Fund. Major goals: To learn the effects of a physician coaching program on referral rates and patient experience. At the end of this study, we will have preliminary data for a future grant submission. We will also have a curriculum that could be implemented in medical training programs that could be evaluated. The principal investigator is Evette J. Ludman