James Ralston MD, MPH, is an internal medicine physician and senior investigator in health services and health informatics. His research mission is improving the health and care of patients living with common ongoing illnesses. His current areas of emphasis include understanding and honoring the priorities of patients living with multiple chronic conditions.
Dr. Ralston’s research focuses on developing and evaluating communication technologies that foster continuous care and a closer connection between patients and primary care teams. His commitment to finding effective ways to redesign care spans all stages of research, from project development to complete translation of results into clinical practice.
Examples of Dr. Ralston’s research projects include:
Dr. Ralston is also a University of Washington affiliate professor in health services and biomedical informatics, where he serves on the committees of PhD and master’s degree students.
Leppig KA, Rahm AK, Appelbaum P, Aufox S, Bland ST, Buchanan A, Christensen KD, Chung WK, Wright-Clayton E, Crosslin D, Denny J, DeVange S, Gordon A, Green RC, Hakonarson H, Harr MH, Henrikson NB, Hoell C, Holm IA, Kullo IJ, Jarvik GP, Lammers PE, Larson EB, Lindor NM, Marasa M, Myer MF, Perez E, Peterson JF, Pratap S, Prows CA, Ralston JD, Rasouly HM, Roden DM, Sharp RR, Singh R, Shaibi G, Smith ME, Sturm A, Thiese HA, Van Driest SL, Williams J, Williams MS, Wynn J, Zawatsky CL, Weisner GL. The reckoning: the return of genomic results to 1444 participants across the eMERGE3 Network. Genet Med. 2022 Feb 22:S1098-3600(22)00031-4. doi: 10.1016/j.gim.2022.01.015. Online ahead of print. PubMed
Schuttner L, Hockett Sherlock S, Simons C, Ralston JD, Rosland AM, Nelson K, Lee JR, Sayre G. Factors affecting primary care physician decision-making for patients with complex multimorbidity: a qualitative interview study. BMC Prim Care. 2022;23(1):25. doi: 10.1186/s12875-022-01633-x. PubMed
McCloskey JK, Ellis JL, Uratsu CS, Drace ML, Ralston JD, Bayliss EA, Grant RW. Accounting for social risk does not eliminate race/ethnic disparities in COVID-19 infection among insured adults: a cohort study. J Gen Intern Med. 2022 Feb 2:1-8. doi: 10.1007/s11606-021-07261-y. [Epub ahead of print]. PubMed
Tuzzio L, O'Meara ES, Holden E, Parchman ML, Ralston JD, Powell JA, Baldwin LM. Barriers to implementing cardiovascular risk calculation in primary care: alignment with the Consolidated Framework for Implementation Research. Am J Prev Med. 2021 Feb;60(2):250-257. doi: 10.1016/j.amepre.2020.07.027. Epub 2020 Dec 3. PubMed
Bell SK, Bourgeois F, DesRoches CM, Dong J, Harcourt K, Liu SK, Lowe E, McGaffigan P, Ngo LH, Novack SA, Ralston JD, Salmi L, Schrandt S, Sheridan S, Sokol-Hessner L, Thomas G, Thomas EJ. Filling a gap in safety metrics: development of a patient-centred framework to identify and categorise patient-reported breakdowns related to the diagnostic process in ambulatory care. BMJ Qual Saf. 2021 Oct 16:bmjqs-2021-013672. doi: 10.1136/bmjqs-2021-013672. Online ahead of print. PubMed
Tchesnokova V, Kulasekara H, Larson L, Bowers V, Rechkina E, Kisiela D, Sledneva Y, Choudhury D, Maslova I, Deng K, Kutumbaka K, Geng H, Fowler C, Greene D, Ralston J, Samadpour M, Sokurenko E. Acquisition of the L452R mutation in the ACE2-binding interface of Spike protein triggers recent massive expansion of SARS-CoV-2 variants. J Clin Microbiol. 2021 Aug 11:JCM0092121. doi: 10.1128/JCM.00921-2. Online ahead of print. PubMed
Tuzzio L, Berry AL, Gleason K, Barrow J, Bayliss EA, Gray MF, Delate T, Bermet Z, Uratsu C, Grant RW, Ralston JD. Aligning care with the personal values of patients with complex care needs. Health Serv Res. 2021 Aug 6. doi: 10.1111/1475-6773.13862. [Epub ahead of print]. PubMed
Henrikson NB, Blasi P, Figueroa Gray M, Tiffany BT, Scrol A, Ralston JD, Fullerton SM, Lim CY, Ewing J, Leppig KA. Patient and family preferences on health system-led direct contact for cascade screening. J Pers Med. 2021;11(6):538. doi: 10.3390/jpm11060538. PubMed
Khan SS, Hoell C, Castillo LM, Connolly JJ, Crosslin DR, Chung WK, Gordon AS, Harr M, Jarvik GP, Kullo I, Larson EB, Leppig KA, Manolio T, Pacheco JA, Ralston JD, Puckelwartz MJ, Smith ME, Wells Q, McNally EM, Rasmussen-Torvik LJ. Practice patterns after return of rare variants associated with cardiomyopathy in the Electronic Medical Records and Genomics Network. Circ Heart Fail. 2021 May;14(5):e008155. doi: 10.1161/CIRCHEARTFAILURE.120.008155. Epub 2021 May 6. PubMed
Ralston JD, Yu O, Penfold RB, Gundersen G, Ramaprasan A, Schartz EM. Changes in clinician attitudes toward sharing visit notes: surveys pre- and post-implementation. J Gen Intern Med. 2021 Apr 22;1-7. doi: 10.1007/s11606-021-06729-1. Online ahead of print. PubMed
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All Washington members are invited to be part of research that could improve health for millions.
The Valuing Important Things in Active Lives (VITAL) study is a three-year project funded by the Agency for Healthcare Research and quality.
Learn about the VITAL study.
Medscape, April 29, 2021