Lisa A. Jackson, MD, MPH

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“Kaiser Permanente Washington gives us nearly unlimited potential to address vaccine effectiveness and safety questions of national and international importance.”

Lisa A. Jackson, MD, MPH

Senior Investigator, Kaiser Permanente Washington Health Research Institute
Physician, Washington Permanente Medical Group, Internal Medicine

Biography

Lisa A. Jackson, MD, MPH, is an internist and infectious disease epidemiologist who has conducted clinical and epidemiologic studies of vaccine safety and efficacy since 1991. Dr. Jackson is the Kaiser Permanente Washington Health Research Institute (KPWHRI) principal investigator (PI) for the Vaccine Safety Datalink Project sponsored by the Centers for Disease Control and Prevention (CDC). She is also PI of the KPWHRI Vaccine and Treatment Evaluation Unit network site—one of nine network sites that the National Institutes of Health sponsors.

Dr. Jackson has written more than 200 peer-reviewed publications and 14 book chapters. She is a past member of the Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee and the National Vaccine Program Office’s National Vaccine Advisory Committee.

After receiving her medical degree from the University of Virginia School of Medicine, in Charlottesville, Dr. Jackson earned her Master of Public Health (MPH) degree at the University of Washington (UW) School of Public Health. She completed her internal medicine residency training at the UW School of Medicine and served as an epidemic intelligence officer and preventive medicine resident at the CDC.

Research interests and experience

  • Vaccines & Infectious Diseases

    Vaccine  safety; influenza vaccine effectiveness in the elderly; methodologic issues in  vaccine effectiveness evaluations; pneumococcal polysaccharide vaccine  effectiveness; pneumococcal conjugate vaccine immunogenicity in the elderly;  epidemiology of E. coli bacteremia; epidemiology of community-acquired  pneumonia

 

Recent publications

Schmoele-Thoma B, Jackson LA, Greenberg RN, Frenck R, Gurtman A, Sundaraiyer V, Gruber WC, Scott DA, Isturiz RE. Immunogenicity of 13-valent pneumococcal conjugate vaccine in immunocompetent older adults with stable underlying medical conditions. J Vaccines Immun. 2015;3:7-12.

McNeil MM, Weintraub ES, Duffy J, Sukumaran L, Jacobsen SJ, Klein NP, Hambidge SJ, Lee GM, Jackson LA, Irving SA, King JP, Kharbanda EO, Bednarczyk RA, DeStefano F. Risk of anaphylaxis after vaccination in children and adults. J Allergy Clin Immunol. 2016 Mar;137(3):868-78. doi: 10.1016/j.jaci.2015.07.048. Epub 2015 Oct 6.

Frey SE, Wald A, Edupuganti S, Jackson LA, Stapleton JT, Sahly HE, El-Kamary SS, Edwards K, Keyserling H, Winokur P, Keitel W, Hill H, Goll JB, Chaplin P, Belshe RB; DMID - MVA Study Group, Anderson EL, Graham IL, Johnston C, Mulligan M, Rouphael N, Atmar R, Patel S, Chen W, Kotloff K, Creech CB. Comparison of lyophilized versus liquid modified vaccinia Ankara (MVA) formulations and subcutaneous versus intradermal routes of administration in healthy vaccinia-naïve subjects. Vaccine. 2015 Sep 22;33(39):5225-34. doi: 10.1016/j.vaccine.2015.06.075. Epub 2015 Jul 2. PubMed

Jackson ML, Bellamy A, Wolff M, Hill H, Jackson LA. Low-dose aspirin use does not diminish the immune response to monovalent H1N1 influenza vaccine in older adults. Epidemiol Infect. 2016 Mar;144(4):768-71. doi: 10.1017/S0950268815002058. Epub 2015 Sep 2. PubMed

Keitel WA, Jackson LA, Edupuganti S, Winokur PL, Mulligan MJ, Thornburg NJ, Patel SM, Rouphael NG, Lai L, Bangaru S, McNeal MM, Bellamy AR, Hill HR; VTEU H3N2v Vaccine Study Work Group. Safety and immunogenicity of a subvirion monovalent unadjuvanted inactivated influenza A(H3N2) variant vaccine in healthy persons =18 years old. J Infect Dis. 2015 Aug 15;212(4):552-61. doi: 10.1093/infdis/jiv056. Epub 2015 Feb 3.

Jackson ML, Jackson LA, Kieke B, McClure D, Gaglani M, Murthy K, Malosh R, Monto A, Zimmerman RK, Foppa IM, Flannery B, Thompson MG. Incidence of medically attended influenza infection and cases averted by vaccination, 2011/2012 and 2012/2013 influenza seasons. Vaccine. 2015 Sep 22;33(39):5181-7. doi:10.1016/j.vaccine.2015.07.098. Epub 2015 Aug 11. PubMed

Jackson ML, Peterson D, Nelson JC, Greene SK, Jacobsen SJ, Belongia EA, Baxter R, Jackson LA. Using winter 2009-2010 to assess the accuracy of methods which estimate influenza-related morbidity and mortality. Epidemiol Infect. 2015 Aug;143(11):2399-407. doi: 10.1017/S0950268814003276. Epub 2014 Dec 12.

Sukumaran L, McCarthy NL, Li R, Weintraub E, Jacobsen SJ, Hambidge SJ, Jackson LA, Naleway AL, Chan B, Tao B, Gee J. Demographic characteristics of members of the Vaccine Safety Datalink (VSD): a comparison with the United States population. Vaccine. 2015 Jul 22. pii: S0264-410X(15)00984-6. doi: 10.1016/j.vaccine.2015.07.037. [Epub ahead of print]. PubMed

Jackson LA, Campbell JD, Frey SE, Edwards KM, Keitel WA, Kotloff KL, Berry AA, Graham I, Atmar RL, Creech CB, Thomsen IP, Patel SM, Gutierrez AF, Anderson EL, El Sahly HM, Hill H, Noah DL, Bellamy AR. Effect of varying doses of a monovalent H7N9 influenza vaccine with and without AS03 and MF59 adjuvants on immune response: a randomized clinical trial. JAMA. 2015;314(3):237-46. doi: 10.1001/jama.2015.7916. PubMed

McLean HQ, Thompson MG, Sundaram ME, Kieke VA, Gaglani M, Murthy K, Piedra PA, Zimmerman RK, Nowalk MP, Raviotta JM, Jackson ML, Jackson L, Ohmit SE, Petrie JG, Monto AS, Meece JK, Thaker SN, Clippard JR, Spencer SM, Fry AM, Belongia EA. Influenza vaccine effectiveness in the United States during 2012-13: variable protection by age and virus type. J Infect Dis. 2015 May 15;211(10):1529-40. doi: 10.1093/infdis/jiu647. Epub 2014 Nov 18. PubMed

 

director's note

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Research versus COVID-19

From clinical trials to technical support, Dr. Rita Mangione-Smith describes how Kaiser Permanente Washington researchers are fighting the novel coronavirus.

research

Jennifer Haller, a clinical trial volunteer, receives the first-ever injection of an investigational vaccine for the coronavirus. Credit: Ted S. Warren / AP Photos

Kaiser Permanente launches first coronavirus vaccine trial

On March 16, 4 volunteers received an injection of an mRNA vaccine for COVID-19 in an NIH-funded trial in Seattle.

KPWHRI In the Media

Kaiser Permanente launches first coronavirus vaccine trial

Volunteers fight virus by testing new experimental vaccine

Associated Press, Mar 16, 2020

research

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Clinical trial of H7N9 bird flu vaccine starts at KPWHRI

Dr. Lisa A. Jackson leads national trial to explore improving immune responses to the vaccine.

Read it in News and Events.

KPWHRI in the Media

Vaccine against new coronavirus

Clinical trials for novel coronavirus vaccine will take place at Seattle research institute

Seattle Times, Feb. 26, 2020