Preventive Medicine

“To help patients avoid the suffering of serious illnesses and injury, we’re seeking the most innovative ways to make screening and health promotion a part of everyday medical practice.”

David C. Grossman, MD, MPH
Kaiser Permanente Washington Health Research Institute Senior Investigator
Kaiser Permanente Washington Medical Director for Population & Purchaser Strategy
Washington Permanente Medical Group, Pediatrics

Research overview

Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping suffering and tragedy from ever happening. Yet that’s the goal of research on preventive care.

Most Kaiser Permanente Washington scientists study prevention—whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.

Examples include research in areas such as:

Immunization

We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, in order to improve their uptake.

Drug safety

We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Mini-Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.

Screening

Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.

Health promotion

Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.

Value-based benefit design

By evaluating Kaiser Permanente Washington’s innovative approaches to health insurance design, we finding our how health benefits may encourage healthy behaviors, improve health outcomes, and reduce costs.

Much of our prevention-related research is conducted in collaboration with the Kaiser Permanente Washington Department of Preventive Care (DPC), a subspecialty group within Kaiser Permanente Washington’s medical staff. DPC is led by Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigators David C. Grossman, MD, MPH, Kaiser Permanente Washington medical director for population and purchaser strategy, and Paula Lozano, MD, MPH, Kaiser Permanente Washington’s assistant medical director for preventive care. Both pediatricians, Drs. Grossman and Lozano work with the medical staff and others to find innovative ways to design, promote, deliver, and evaluate preventive care and health promotion services for the organization’s 600,000 members. By doing so, they’re bringing value to Kaiser Permanente Washington patients while discovering new approaches that can be disseminated to health care systems nationwide.

KPWHRI researchers also serve the public by producing reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. KPWHRI does this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 11 such centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.

Recent publications on Preventive Medicine

Kemper AR, Fan T, Grossman DC, Phipps MG. Gaps in evidence regarding iron-deficiency anemia in pregnant women and young children: summary of US Preventive Services Task Force recommendations. Am J Clin Nutr. 2017 Oct 25. pii: ajcn155788. doi: 10.3945/ajcn.117.155788. [Epub ahead of print]. PubMed

US Preventive Services Task Force, Grossman DC, Curry SJ, Owens DK, Barry MJ, Davidson KW, Doubeni CA, Epling JW Jr, Kemper AR, Krist AH, Kurth AE, Landefeld CS, Mangione CM, Phipps MG, Silverstein M, Simon MA, Tseng CW. Vision screening in children aged 6 months to 5 years: US Preventive Services Task Force recommendation statement. JAMA. 2017 Sep 5;318(9):836-844. doi: 10.1001/jama.2017.11260. PubMed

Grossman DC, Curry SJ, Owens DK Guideline recommendations for statin therapy. JAMA. 2017;318(10):963-964. doi: 10.1001/jama.2017.11375. PubMed

Lehavot K, Blosnich JR, Glass JE, Williams EC. Alcohol use and receipt of alcohol screening and brief intervention in a representative sample of sexual minority and heterosexual adults receiving health care. Drug Alcohol Depend. 2017 Oct 1;179:240-246. doi: 10.1016/j.drugalcdep.2017.07.003. Epub 2017 Aug 2. PubMed

Ritvo P, Myers RE, Serenity M, Gupta S, Inadomi JM, Green BB, Jerant A, Tinmouth J, Paszat L, Pirbaglou M, Rabeneck L. Taxonomy for colorectal cancer screening promotion: Lessons from recent randomized controlled trials. Prev Med. 2017;101:229-234. doi: 10.1016/j.ypmed.2016.12.024. Epub 2016 Dec 24. PubMed

Researchers in Preventive Medicine

David C. Grossman, MD, MPH

Senior Investigator, KPWHRI; Senior Associate Medical Director, Market Strategy & Public Policy and Physician, Pediatrics, Washington Permanente Medical Group
206-287-2948
David.C.Grossman@kp.org

Curriculum vitae (CV)

Paula Lozano, MD, MPH

Senior Investigator, KPWHRI; Associate Medical Director for Research and Translation & Physician, Pediatrics, Washington Permanente Medical Group
206-287-2113
Paula.Lozano@kp.org

Curriculum vitae (CV)

Diana S. Buist, PhD, MPH

Director of Research and Strategic Partnerships; Senior Investigator
206-287-2931
Diana.S.Buist@kp.org

Curriculum vitae (CV)

Katharine A. Bradley, MD, MPH

Senior Investigator
206-287-2151
Katharine.A.Bradley@kp.org

Curriculum vitae (CV)

Jessica Chubak, PhD, MBHL

Senior Investigator
206-287-2556
Jessica.Chubak@kp.org

Curriculum vitae (CV)

Dori E. Rosenberg, PhD, MPH

Associate Investigator
206-287-2532
Dori.E.Rosenberg@kp.org

Curriculum vitae (CV)

Karen Wernli, PhD

Associate Investigator
206-287-2934
Karen.J.Wernli@kp.org

Curriculum vitae (CV)

Erin J. Bowles, MPH

Research Associate
206-287-2708
Erin.A.Bowles@kp.org

Curriculum vitae (CV)

Nora Henrikson, PhD, MPH

Assistant Investigator
206-287-4675
Nora.B.Henrikson@kp.org

Curriculum vitae (CV)

Aruna Kamineni, PhD, MPH

Assistant Investigator
206-287-2922
Aruna.S.Kamineni@kp.org

Curriculum vitae (CV)

Melissa L. Anderson, MS

Senior Biostatistician
206-287-2647
Melissa.L.Anderson@kp.org

Curriculum vitae (CV)

Paula R. Blasi, MPH

Research Associate
206-287-2094
Paula.R.Blasi@kp.org

Curriculum vitae (CV)

Leah Tuzzio, MPH

Research Associate
206-287-2109
Leah.Tuzzio@kp.org

Curriculum vitae (CV)

Joseph E. Glass, PhD, MSW

Associate Investigator
206-287-4266
Joseph.E.Glass@kp.org

Curriculum vitae (CV)

Amy K. Lee, MPH

Research Associate
206-287-2827
Amy.K.Lee@kp.org

Curriculum vitae (CV)

Julie E. Richards, PhD, MPH

Research Associate II
206-287-2100
Julie.E.Richards@kp.org

Curriculum vitae (CV)