Erin Bowles, MPH

Bowles_Erin_J_205x293.jpg

“At KPWHRI, we have access to extensive data on cancer care. I'm using the data to learn how to improve the experiences of cancer patients and their families.”

Erin Bowles, MPH

Senior Research Associate, Kaiser Permanente Washington Health Research Institute

Biography

Epidemiologist Erin Bowles, MPH, is looking at cancer and aging from many different perspectives. Her research brings new insight into breast cancer risk factors, treatment, and survivorship, while helping improve cancer care for patients and families.

Ms. Bowles received an R50 mid-career research award from the National Cancer Institute (NCI). This award is given to cancer researchers who have demonstrated successes and contributions to cancer researcher as a non-principal investigator. As a key member of two large cancer collaborations—the NCI's Breast Cancer Surveillance Consortium and the Health Care Systems Cancer Research Network (CRN)—Ms. Bowles has developed diverse expertise that includes reading mammograms for breast density and using administrative data to understand patterns of care in cancer treatment.

Her current work includes:

  • a multi-site CRN study led by an investigator at Memorial Sloan Kettering Cancer Center to understand how obesity affects chemotherapy treatment dosing and risks of recurrence and toxicity in women with breast cancer;
  • helping investigators from Kaiser Permanente Northern California and the University of California (UC) San Francisco and UC Davis understand imaging trends in children and pregnant women, and subsequent risks of leukemia associated with ionizing radiation from imaging exams; and
  • working with Kaiser Permanente Washington Health Research Institute (KPWHRI) investigator Diana Buist, PhD, and investigators from the NCI and Kaiser Permanente Colorado to study how mammographic breast density and radiation treatment are associated with second cancers in women with previous breast cancer.

Ms. Bowles' experience working with large cancer cohorts has provided her with expertise in data collection and management for other subject areas. She is a co-investigator on the Adult Changes in Thought study team, and oversees their living laboratory and data sharing for aging research, along with an annual research symposium. Finally, she is a member of the Kaiser Permanente Research Affiliates Evidence-based Practice Center and has participated in systematic evidence reviews for the U.S. Preventive Services Task Force.

Research interests and experience

  • Cancer

    Breast cancer; colorectal cancer; multiple myeloma; thyroid cancer; pancreatic cancer; biostatistics; epidemiology; mammography; mammographic breast density; cancer treatment; cancer screening and surveillance; automated data collection; quality of care; medication use; care coordination; administrative data

  • Health Services & Economics

    Access to care; health disparities; health outcomes research; quality of life; measurement of change in health care systems; practice variation

  • Women's Health

    Menopause; hormone replacement therapy (HRT); breast cancer

  • Aging & Geriatrics

    Cognitive health and dementia; biostatistics; epidemiology; medication use; cancer

Recent publications

Henrikson NB, Aiello Bowles EJ, Blasi PR, Morrison CC, Nguyen M, Pillarisetty VG, Lin JS. Screening for pancreatic cancer: updated evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2019;322(5):445-454. doi: 10.1001/jama.2019.6190. PubMed

Kwan ML, Miglioretti DL, Marlow EC, Aiello Bowles EJ, Weinmann S, Cheng SY, Deosaransingh KA, Chavan P, Moy LM, Bolch WE, Duncan JR, Greenlee RT, Kushi LH, Pole JD, Rahm AK, Stout NK, Smith-Bindman R. Trends in medical imaging during pregnancy in the United States and Ontario, Canada, 1996 to 2016. JAMA Netw Open. 2019;2(7):e197249. doi: 10.1001/jamanetworkopen.2019.7249. PubMed

Brooks GA, Uno H, Aiello Bowles EJ, Menter AR, O'Keeffe-Rosetti M, Tosteson ANA, Ritzwoller DP, Schrag D. Hospitalization risk during chemotherapy for advanced cancer: development and validation of risk stratification models using real-world data. JCO Clin Cancer Inform. 2019;(3):1-10. doi: 10.1200/CCI.18.00147. PubMed

Bowles EJA, Yu O, Ziebell R, Chen L, Boudreau DM, Ritzwoller DP, Hubbard RA, Boggs JM, Burnett-Hartman AN, Sterrett A, Fujii M, Chubak J. Cardiovascular medication use and risks of colon cancer recurrences and additional cancer events: a cohort study. BMC Cancer. 2019;19(1):270. doi: 10.1186/s12885-019-5493-8. PubMed

Aiello Bowles EJ, Crane PK, Walker RL, Chubak J, LaCroix AZ, Anderson ML, Rosenberg D, Keene CD, Larson EB. Cognitive resilience to Alzheimer's disease pathology in the human brain.  J Alzheimers Dis. 2019 Mar 18. doi: 10.3233/JAD-180942. [Epub ahead of print]. PubMed

Knerr S, Bowles EJA, Leppig KA, Buist DSM, Gao H, Wernli KJ. Trends in BRCA test utilization in an integrated health system, 2005-2015. J Natl Cancer Inst. 2019 Feb 8. pii: 5310095. doi: 10.1093/jnci/djz008. [Epub ahead of print]. PubMed

 

cancer research

SusanKarenDianneMary-1col.jpg

Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

Breast Cancer Surveillance

Kaiser Permanente Washington Breast Cancer Surveillance Registry

Kaiser Permanente Washington has been part of the national Breast Cancer Surveillance Consortium since 1994. Learn about the Kaiser Permanente Washington Breast Cancer Surveillance Registry here.

preventative care

HPV-home-test_Buist-Blog_1col.jpg

Cervical cancer screening study explores home-based options

Could at-home kits help save more lives? Drs. Diana Buist and Rachel Winer are on a journey to find out.
 

recent research

ACT-study-brain-MRI_1col.jpg

New grant will help retrieve brain MRI scan data

National Institute on Aging awards more than $3 million to Adult Changes in Thought (ACT) study for 5 years.