Research is often lauded for finding life-saving treatments for diseases like cancer or diabetes. But consider the impact of preventing such illnesses from developing in the first place. It’s hard to describe the value of stopping illness or injury from happening. Yet that’s the goal of research on preventive care.
Most Kaiser Permanente Washington scientists study prevention, whether their work focuses on promoting health by influencing individual behavior, building sound prevention services into everyday clinical care, designing smart health coverage, or all three. By conducting their research at Kaiser Permanente Washington—which combines care and coverage—our researchers have access to data from a large, stable population over time, allowing them to discover which approaches to prevention work best.
Examples include research in areas such as:
A team of researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) produces reviews of scientific evidence that policymakers at the Centers for Medicare & Medicaid Services and the U.S. Preventive Services Task Force and others use in health care decision-making. We do this work as part of the Kaiser Permanente Research Affiliates Evidence-based Practice Center, one of 13 centers nationwide that are sponsored by the federal Agency for Healthcare Research and Quality.
We’re improving the safety and effectiveness of vaccines through clinical trials, and we’re monitoring how well each year’s new flu vaccines are working. In addition, we’re studying ways to better inform parents about the benefits and potential harms of childhood vaccines, to improve their uptake.
We’re working on several fronts to help ensure the safety of prescription drugs and other medical treatments. For example, we play a leading role in the Food and Drug Administration’s Sentinel program to monitor the safety of medical products through routinely collected electronic health care data. We’re exploring ways to improve the safety of prescribing opioid pain medications. And we often study the safety of drugs commonly used to prevent chronic conditions like heart disease, cancer, and depression.
Prevention also includes screening to detect disease before symptoms appear, to identify and treat disease at an earlier stage. Our research is improving the effectiveness of cancer screening programs so people get the appropriate tests when needed based on their particular risks. Our research is also aimed at improving clinical screening for behavioral risks such as smoking, suicidal thoughts, alcohol use disorders, and poor eating and exercise habits.
Our research in areas such as smoking cessation, healthy diet, and chronic illness care finds new ways to encourage individuals to adopt and maintain healthier lifestyles. At the same time, we’re exploring ways to reach large populations through the use of phone-based programs, websites, and mobile technologies.
Boe LA, Mossavar-Rahmani Y, Sotres-Alvarez D, Daviglus ML, Durazo-Arvizu RA, Thyagarajan B, Kaplan RC, Shaw PA Nutritional blood concentration biomarkers in the Hispanic Community Health Study/Study of Latinos: Measurement characteristics and power 2023 Aug 4;192(8):1288-1303. doi: 10.1093/aje/kwad109. Epub 2023-04-27. PubMed
Lee JM, Ichikawa LE, Wernli KJ, Bowles EJA, Specht JM, Kerlikowske K, Miglioretti DL, Lowry KP, Tosteson ANA, Stout NK, Houssami N, Onega T, Buist DSM Impact of Surveillance Mammography Intervals Less Than One Year on Performance Measures in Women With a Personal History of Breast Cancer 2023 Aug;24(8):729-738. doi: 10.3348/kjr.2022.1038. PubMed
DeSilva MB, Haapala J, Vazquez-Benitez G, Boyce TG, Fuller CC, Daley MF, Getahun D, Hambidge SJ, Lipkind HS, Naleway AL, Nelson JC, Vesco KK, Weintraub ES, Williams JTB, Zerbo O, Kharbanda EO Medically Attended Acute Adverse Events in Pregnant People After Coronavirus Disease 2019 (COVID-19) Booster Vaccination 2023 Jul;142(1):125-129. doi: 10.1097/AOG.0000000000005241. Epub 2023-05-11. PubMed
Sprague BL, Coley RY, Lowry KP, Kerlikowske K, Henderson LM, Su YR, Lee CI, Onega T, Bowles EJA, Herschorn SD, diFlorio-Alexander RM, Miglioretti DL Digital Breast Tomosynthesis versus Digital Mammography Screening Performance on Successive Screening Rounds from the Breast Cancer Surveillance Consortium 2023 Jun;307(5):e223142. doi: 10.1148/radiol.223142. PubMed
Joo YY, Pacheco JA, Thompson WK, Rasmussen-Torvik LJ, Rasmussen LV, Lin FTJ, Andrade M, Borthwick KM, Bottinger E, Cagan A, Carrell DS, Denny JC, Ellis SB, Gottesman O, Linneman JG, Pathak J, Peissig PL, Shang N, Tromp G, Veerappan A, Smith ME, Chisholm RL, Gawron AJ, Hayes MG, Kho AN Multi-ancestry genome- and phenome-wide association studies of diverticular disease in electronic health records with natural language processing enriched phenotyping algorithm 2023 May 17;18(5):e0283553. doi: 10.1371/journal.pone.0283553. Epub 2023-05-17. PubMed
Claire Allen, MPHManager, Collaborative Science |
Melissa L. Anderson, MSPrincipal Collaborative Biostatistician |
Julie Angerhofer, PhD, MPHAssociate Investigator |
Paula R. Blasi, MPHSenior Collaborative Scientist |
Erin J. Bowles, MPHDirector, Collaborative Science |
Katharine A. Bradley, MD, MPHSenior Investigator |
Meagan C. Brown, PhD, MPHAssistant Investigator |
Jessica Chubak, PhDSenior Investigator |
Nicole M. Gatto, PhD, MPHPrincipal Collaborative Scientist |
Nora Henrikson, PhD, MPHAssociate Investigator |
Annie Hoopes, MD, MPHAssistant Investigator |
Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
Theresa E. Matson, PhD, MPHCollaborative Scientist |
Dori E. Rosenberg, PhD, MPHSenior Investigator |
Pamela A. Shaw, PhD, MSSenior Biostatistics Investigator |
Kelsey Stefanik-Guizlo, MPHCollaborative Scientist |
Yu-Ru Su, PhDAssociate Biostatistics Investigator |
Karen Wernli, PhDSenior Investigator |