Research on health informatics at Kaiser Permanente Washington focuses on developing and using health information technology (IT) to transform health care delivery. By testing new paradigms of care that provide more opportunities to engage patients, this research is supplying valuable evidence that is helping shape federal policy and guiding innovative redesign of health care.
“We’re working to understand how to make health IT practical so patients and care teams find it useful and engaging,” explained Kaiser Permanente Washington Health Research Institute (KPWHRI) Senior Investigator James Ralston, MD, MPH. “We want to find ways to use information technologies to support patients and providers together, both inside and outside the office.”
Integral to this support is designing technologies that are user-friendly and meet the needs of both patients and providers. By applying human-centered methods that focus on needs, use, and usability, KPWHRI researchers inform the design of health IT with direct participation from users.
Groundbreaking methodological work by KPWHRI health informatics researchers includes developing natural language processing (NLP) to analyze text such as notes and written reports in electronic health records (EHRs). Assistant Investigator David Carrell, PhD, leads in the area of using NLP and machine learning to identify patient phenotypes, or specific health characteristics such as possible heart disease, risk of opioid overdose, or suggestion of colon cancer. This information can assist researchers in studying how genetics and other factors influence disease.
Other examples of KPWHRI health informatics research include projects using EHRs and secure electronic communications such as:
Examples of KPWHRI research in mobile health (mHealth) and user-centered design include:
“Our studies on using health IT to improve care are showing that we can achieve better outcomes when we shift care from the doctor’s office to where people live: in their homes—and online,” said Senior Investigator Beverly B. Green, MD, MPH.
Milani CJ, Rundell SD, Jarvik JG, Friedly J, Heagerty PJ, Avins A, Nerenz D, Gold LS, Turner JA, Annaswamy T, Nedeljkovic SS, Suri P. Associations of race and ethnicity with patient-reported outcomes and health care utilization among older adults initiating a new episode of care for back pain. Spine. 2017 Nov 20. doi: 10.1097/BRS.0000000000002499. [Epub ahead of print]. PubMed
Gray SL, Walker RL, Dublin S, Yu O, Bowles EJA, Anderson ML, Crane PK, Larson EB. Proton pump inhibitor use and dementia risk: prospective population-based study. J Am Geriatr Soc. 2017 Nov 14. doi: 10.1111/jgs.15073. [Epub ahead of print]. PubMed
Dillon EC, Tuzzio L, Madrid S, Olden H, Greenlee RT. Measuring the impact of patient-engaged research: how a methods workshop identified Critical Outcomes of Research Engagement (COREs). J Patient Cent Res Rev. 2017;4:237-46. doi: 10.17294/2330-0698.1458 PubMed
Solberg LI, Asche SE, Butler JC, Carrell DS, Norton CK, Jarvik JG, Smith-Bindman R, Tillema JO, Whitebird RR, Werner AM, Ziegenfuss JY. Patient centered outcomes measurement: does it require reports from patients? J Patient Cent Res Rev. 2017 Nov 6. 4(4):221-229. PubMed
Lott JP, Boudreau DM, Barnhill RL, Weinstock MA, Knopp E, Piepkorn MW, Elder DE, Knezevich SR, Baer A, Tosteson ANA, Elmore JG. Population-based analysis of histologically confirmed melanocytic proliferations using natural language processing. JAMA Dermatol. 2018 Jan 1;154(1):24-29. doi: 10.1001/jamadermatol.2017.4060. PubMed
![]() James D. Ralston, MD, MPHSenior Investigator |
![]() Beverly B. Green, MD, MPHSenior Investigator |
![]() Katharine A. Bradley, MD, MPHSenior Investigator |
![]() Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
![]() Yates Coley, PhDAssociate Biostatistics Investigator |
![]() Brian D. Williamson, PhDAssistant Biostatistics Investigator |
![]() Annie Hoopes, MD, MPHAssistant Investigator |
![]() Claire Allen, MPHManager, Collaborative Science |