Mental health is a vital part of overall health. But traditional mental health care reaches only a fraction of the millions who could benefit. So, researchers at Kaiser Permanente Washington Health Research Institute (KPWHRI) are finding practical, patient-centered ways to reach people affected by conditions such as depression, bipolar disorder, and anxiety.
“Many of the ideas that are changing American mental health care were first tested here at Kaiser Permanente Washington,” said Gregory Simon, MD, MPH, senior investigator at KPWHRI and a Kaiser Permanente Washington psychiatrist. “We’re now working to spread those innovations to large health systems across the country.”
Some of the mental health research group’s current projects include:
Innovative patient-centered mental health programs developed at KPWHRI include:
“We are partnering with health care leaders at Kaiser Permanente Washington and other health systems to test innovative programs and implement treatments that work,” Simon said. “We want ‘learning health care system’ to be more than a slogan.”
Curtis LH, Morain S, O'Rourke PP, Staman K, Jarvik JG, Cheville A, Dailey DL, Sluka KA, Heagerty P, Melnick ER, Chakraborty H, Tulsky JA, Volandes A, Simon GE. Monitoring in pragmatic trials lessons from the NIH pragmatic trials collaboratory. Contemp Clin Trials. 2025 May;152:107866. doi: 10.1016/j.cct.2025.107866. Epub 2025 Feb 25. PubMed
Simon GE, Garner BR, Smith JD, Wyman PA, Matson TE, Chin-Purcell L, Cero I, Vermeer W, Johnson KA, Prado G, Brown CH. Rollout trial designs in implementation research are often necessary and sometimes preferred. Implement Sci. 2025;20(1):11. doi: 10.1186/s13012-025-01422-x. PubMed
Penfold RB, Yoo HI, Richards JE, Crossnohere NL, Johnson E, Pabiniak CJ, Renz AD, Campoamor NB, Simon GE, Bridges JFP. Acceptability of linking individual credit, financial, and public records data to healthcare records for suicide risk machine learning models. JAMIA Open. 2024 Oct 21;7(4):ooae113. doi: 10.1093/jamiaopen/ooae113. eCollection 2024. PubMed
Rossom RC, Crain AL, Bart G, Richards JE, Boggs JM, O'Connor PJ, Borgert-Spaniol C, Kane S, Hooker SA. Randomized pilot of a clinical decision support tool to increase suicide screening for at-risk primary care patients with opioid use disorder. AJPM Focus. 2024 Oct 2;3(6):100280. doi: 10.1016/j.focus.2024.100280. eCollection 2024. PubMed
Cukor J, Xu Z, Vekaria V, Wang F, Olfson M, Banerjee S, Simon G, Alexopoulos G, Pathak J. Longitudinal trajectories of symptom change during antidepressant treatment among managed care patients with depression and anxiety. Npj Ment Health Res. 2024;3(1):58. doi: 10.1038/s44184-024-00104-8. PubMed
![]() Gregory E. Simon, MD, MPHSenior Investigator |
![]() Ben Balderson, PhDSenior Collaborative Scientist |
![]() Katharine A. Bradley, MD, MPHSenior Investigator |
![]() Paula Lozano, MD, MPHSenior Investigator; Director, ACT Center |
![]() Robert Penfold, PhDSenior Investigator |
![]() Susan M. Shortreed, PhDSenior Biostatistics Investigator |
![]() Dori E. Rosenberg, PhD, MPHSenior Investigator |
![]() Gwen Lapham, PhD, MPH, MSWAssistant Investigator |
![]() Jennifer F. Bobb, PhDAssociate Biostatistics Investigator |
![]() Joseph E. Glass, PhD, MSWSenior Investigator |
![]() Julie E. Richards, PhD, MPHAssociate Investigator |
![]() Paige D. Wartko, PhD, MPHSenior Collaborative Scientist |
![]() Yates Coley, PhDAssociate Biostatistics Investigator |
![]() Abisola Idu, MS, MPHCollaborative Biostatistician |
![]() Eric Johnson, MSSenior Collaborative Biostatistician |
![]() Rod L. Walker, MSPrincipal Collaborative Biostatistician |
![]() Robert D. Wellman, MSPrincipal Collaborative Biostatistician |
![]() Leah K. Hamilton, PhDSenior Collaborative Scientist |
![]() Brian D. Williamson, PhDAssistant Biostatistics Investigator |
![]() Rosemary Meza, PhD, MSCollaborative Scientist |
![]() Morgan Justice, MACollaborative Scientist |
![]() Theresa E. Matson, PhD, MPHCollaborative Scientist |
![]() Lily N. Shapiro, PhDCollaborative Scientist |
Paul Crane, MD, MPH
Professor, Internal Medicine
University of Washington
Patrick Heagerty, PhD
Professor and Chair, Department of Biostatistics
University of Washington
Laura P. Richardson, MD, MPH
Adolescent Medicine
Seattle Children's Hospital
Professor, Department of Pediatrics
University of Washington
Noah R. Simon, PhD
Assistant Professor, Biostatistics
University of Washington
Principal Investigator, Therapeutics Development
Seattle Children’s Research Institute
Emily Williams, PhD, MPH
Investigator
Health Services Research & Development
VA Puget Sound Health Care System