Laura E. Ichikawa, MS

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"KPWHRI provides a great opportunity to collaborate with multidisciplinary teams and provide biostatistical support to improve patient health."

Laura E. Ichikawa, MS

Senior Biostatistician, Kaiser Permanente Washington Health Research Institute

Biography

With more than 25 years at Kaiser Permanente Washington Health Research Institute (KPWHRI), Laura Ichikawa, MS, is known for her analytical skills, attention to detail regarding study design and data management, and expertise in data visualization. Her experience includes observational studies, randomized controlled trials, case-control studies, and multisite analyses.

Ms. Ichikawa is primarily focused on breast cancer and women’s health. She is involved in two large, multisite National Cancer Institute-funded projects: the Statistical Coordinating Center for the Breast Cancer Surveillance Consortium (BCSC) and a colorectal research site for Population-based Research to Optimize the Screening Process (PROSPR). Much of her work with the BCSC has been evaluating mammography performance and use of other imaging modalities such as MRI, or magnetic resonance imaging, especially after a breast cancer diagnosis. Ms. Ichikawa also participated in collaborative research through the Cancer Research Network, including a widely publicized 2004 study that linked not having screening mammograms to late-stage breast cancer. More recently, this work examined the association of chemotherapy use with peripheral neuropathy. Ms. Ichikawa is excited to continue her work in breast cancer research, including in screening, treatment, surveillance, and survival.

Ms. Ichikawa's research with retired KPWHRI Senior Investigator Delia Scholes, PhD, includes studies examining bone loss associated with the injectable hormonal contraceptive Depo-Provera in 2002 and 2005 and oral contraceptives in 2011. She continues to work in areas of women’s health and contraceptive methods.

Ms. Ichikawa is a member of the American Statistical Association and its Puget Sound chapter.

Research interests and experience

 

Recent publications

Miglioretti DL, Ichikawa L, Smith RA, Bassett LW, Feig SA, Monsees B, Parikh JR, Rosenberg RD, Sickles EA, Carney PA. Criteria for identifying radiologists with acceptable screening mammography interpretive performance on basis of multiple performance measures. AJR Am J Roentgenol. 2015;204(4):W486-91. doi: 10.2214/AJR.13.12313. PubMed

Allison KH, Abraham LA, Weaver DL, Tosteson AN, Nelson HD, Onega T, Geller BM, Kerlikowske K, Carney PA, Ichikawa LE, Buist DS, Elmore JG. Trends in breast biopsy pathology diagnoses among women undergoing mammography in the United States: a report from the Breast Cancer Surveillance Consortium. Cancer. 2015 Jan 20. doi: 10.1002/cncr.29199. [Epub ahead of print]. PubMed

Allison KH, Abraham LA, Weaver DL, Tosteson AN, Nelson HD, Onega T, Geller BM, Kerlikowske K, Carney PA, Ichikawa LE, Buist DS, Elmore JG. Trends in breast tissue sampling and pathology diagnoses among women undergoing mammography in the U.S.: a report from the Breast Cancer Surveillance Consortium. Cancer. 2015 Jan 20. doi: 10.1002/cncr.29199. [Epub ahead of print].

Lee CI, Ichikawa L, Rochelle MC, Kerlikowske K, Miglioretti DL, Sprague BL, DeMartini WB, Wernli KJ, Joe BN, Yankaskas BC, Lehman CD. Breast MRI BI-RADS assessments and abnormal interpretation rates by clinical indication in US community practices. Acad Radiol. 2014 Nov;21(11):1370-6. doi: 10.1016/j.acra.2014.06.003. Epub 2014 Aug 7. PubMed

Spangler L, Ichikawa LE, Hubbard RA, Operskalski B, LaCroix AZ, Ott SM, Scholes D. A comparison of self-reported oral contraceptive use and automated pharmacy data in perimenopausal and early postmenopausal women. Ann Epidemiol. 2015 Jan;25(1):55-9. doi: 10.1016/j.annepidem.2014.10.009. Epub 2014 Oct 16. PubMed

Wernli KJ, DeMartini WB, Ichikawa L, Lehman C, Onega TL, Kerlikowske K, Gellar BM, Hofmann M, Yankaskas BC; for the Breast Cancer Surveillance Consortium. Patterns of breast magnetic resonance imaging use in community practice. JAMA Intern Med. 2014 Jan;174(1):125-32. doi: 10.1001/jamainternmed.2013.11963. Epub 2013 Nov 18. PubMed

Carney PA, Parikh J, Sickles EA, Feig SA, Monsees B, Bassett LW, Smith RA, Rosenberg R, Ichikawa L, Wallace J, Tran K, Miglioretti DL. Diagnostic mammography: identifying minimally acceptable interpretive performance criteria. Radiology. 2013 May;267(2):359-67. doi: 10.1148/radiol.12121216. Epub 2013 Jan 7. PubMed

Gierach GL, Ichikawa L, Kerlikowske K, Brinton LA, Farhat GN, Vacek PM, Weaver DL, Schairer C, Taplin SH, Sherman ME. Relationship between mammographic density and breast cancer death in the Breast Cancer Surveillance Consortium. J Natl Cancer Inst. 2012;104(16):1218-27. Epub 2012 Aug 21. PubMed

Grafton J, Ott S, Endres J, Kratohvil C, Hubbard R, Ichikawa L, St John J, Operskalski B, Spangler L, Anderson J, Rillamas-Sun E, LaCroix A, Scholes D. Ps1-52: Charting the course: adjudicating fractures in network enrollees using the electronic medical record. Clin Med Res. 2012;10(3):165. PubMed

Rillamas-Sun E, Ichikawa L, LaCroix A, Ott S, Hubbard R, Spangler L, Scholes D. Ps2-28: The association of body composition indices and hormonal contraceptive use in adolescent and young adult women. Clin Med Res. 2012;10(3):186. PubMed

 

cancer research

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Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

study results

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No need to follow up simple ovarian cysts

New KPWHRI study shows that women with simple cysts are not at increased risk of ovarian cancer.

aging & geriatrics

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Study finds various treatments can reduce vaginal discomfort from sex

Dr. Katherine Newton co-wrote JAMA Internal Medicine paper comparing vaginal estrogen, moisturizer, and placebo gel.