Vaccines save lives by protecting people against infectious diseases — polio, influenza, and pneumonia to name a few. Kaiser Permanente Washington Health Research Institute (KPWHRI) is working to protect communities through research to continually improve the safety and effectiveness of vaccines for infectious diseases of public health importance.
Central to this work is testing new vaccines against emerging diseases — such as COVID-19. In March 2020, KPWHRI gave the world’s first-ever injection of an investigational vaccine for COVID-19 in a phase 1 clinical trial led by Senior Investigator Lisa A. Jackson, MD, MPH. We continue to be at the forefront of efforts to understand and combat COVID-19. To learn more, see COVID-19 research at KPWHRI.
Successes over 3 decades of KPWHRI vaccine research include:
Our current research projects on vaccines and infectious diseases include:
Ferdinands JM, Fry AM, Reynolds S, Petrie J, Flannery B, Jackson ML, Belongia EA. Intraseason waning of influenza vaccine protection: evidence from the US Influenza Vaccine Effectiveness Network, 2011-12 through 2014-15. Clin Infect Dis. 2016 Dec 29. pii: ciw816. doi: 10.1093/cid/ciw816. [Epub ahead of print]. PubMed
Gaglani M, Pruszynski J, Murthy K, Clipper L, Robertson A, Reis M, Chung JR, Piedra PA, Avadhanula V, Nowalk MP, Zimmerman RK, Jackson ML, Jackson LA, Petrie JG, Ohmit SE, Monto AS, McLean HQ, Belongia EA, Fry AM, Flannery B. Influenza vaccine effectiveness against the 2009 pandemic A(H1N1) virus differed by vaccine type during 2013-14 in the United States. J Infect Dis. 2016 May 15;213(10):1546-56. doi: 10.1093/infdis/jiv577. Epub 2016 Jan 6. PubMed
Hood N, Flannery B, Gaglani M, Beeram M, Wernli K, Jackson ML, Martin ET, Monto AS, Zimmerman R, Raviotta J, Belongia EA, McLean HQ, Kim S, Patel M, Chung J. Influenza vaccine effectiveness among children: 2011-2020. Pediatrics. 2023 Mar 24;e2022059922. doi: 10.1542/peds.2022-059922. Online ahead of print. PubMed
Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Sheth SS, Zhu J, Naleway AL, Klein NP, Hechter R, Daley MF, Donahue JG, Jackson ML. Risk of spontaneous abortion after inadvertent human papillomavirus vaccination in pregnancy. Obstet Gynecol. 2018 Jun 6. doi: 10.1097/AOG.0000000000002694. [Epub ahead of print]. PubMed
Leyenaar JK, McDaniel CE, Arthur KC, Stevens CA, St Ivany AR. Healthcare quality for acute illness during the COVID-19 pandemic: a multisite qualitative analysis. Pediatr Qual Saf. 2021 Sep 24;6(5):e476. doi: 10.1097/pq9.0000000000000476. eCollection 2021 Sep-Oct. PubMed
Lisa A. Jackson, MD, MPHSenior Investigator |
Jennifer C. Nelson, PhDDirector, Biostatistics; Senior Investigator |
Andrea J. Cook, PhDSenior Biostatistics Investigator |
Sascha Dublin, MD, PhDSenior Investigator |
Onchee Yu, MSPrincipal Collaborative Biostatistician |
Robert D. Wellman, MSPrincipal Collaborative Biostatistician |
Clarissa Hsu, PhDAssociate Investigator |
Brian D. Williamson, PhDAssistant Biostatistics Investigator |
Noorie Hyun, PhDAssociate Biostatistics Investigator |
Pamela A. Shaw, PhD, MSSenior Biostatistics Investigator |
Annie Piccorelli, PhDSenior Collaborative Biostatistician |
Doug Opel, MD, MPH
University of Washington (UW) Department of Bioethics and Humanities; UW Department of Pediatrics; UW Medical Center
John Dunn, MD, MPH
Kaiser Foundation Health Plan of Washington
Elizabeth Lin, MD, MPH
Kaiser Foundation Health Plan of Washington Family Practice;
Kaiser Permanente Washington Health Research Institute