Vaccines save lives by protecting people against infectious diseases—polio, influenza, and malaria to name a few. Kaiser Permanente Washington Health Research Institute (KPWHRI) is working to protect communities through research to continually improve the safety and effectiveness of vaccines and other treatments for infectious diseases as well as cancer. We also test new vaccines that may stop the threat of emerging diseases such as the novel coronavirus (SARS-CoV-2), which causes COVID-19.
Our research projects on vaccines and infectious diseases include:
Successes over 3 decades of KPWHRI research on vaccines and preventing and treating infectious disease include:
Flannery B, Meece JK, Williams JV, Martin ET, Gaglani M, Jackson ML, Talbot HK. Systematic testing for influenza and COVID-19 among patients with respiratory illness. Clin Infect Dis. 2020 Jul 20:ciaa1023. doi: 10.1093/cid/ciaa1023. [Epub ahead of print]. PubMed
Munoz FM, Patel SM, Jackson LA, Swamy GK, Edwards KM, Frey SE, Petrie CR, Sendra EA, Keitel WA. Safety and immunogenicity of three seasonal inactivated influenza vaccines among pregnant women and antibody persistence in their infants. Vaccine. 2020;38(33):5355-5363. doi: 10.1016/j.vaccine.2020.05.059. Epub 2020 Jun 19. PubMed
Jackson LA, Anderson EJ, Rouphael NG, Roberts PC, Makhene M, Coler RN, McCullough MP, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott A, Flach B, Doria-Rose NA, Corbett KS, Morabito KM, O'Dell S, Schmidt SD, Swanson PA 2nd, Padilla M, Mascola JR, Neuzil KM, Bennett H, Sun W, Peters E, Makowski M, Albert J, Cross K, Buchanan W, Pikaart-Tautges R, Ledgerwood JE, Graham BS, Beigel JH; mRNA-1273 Study Group. An mRNA vaccine against SARS-CoV-2 - preliminary report. N Engl J Med. 2020 Nov 12;383(20):1920-1931. doi: 10.1056/NEJMoa2022483. Epub 2020 Jul 14. PubMed
Dublin S, Walker RL, Floyd JS, Shortreed SM, Fuller S, Albertson-Junkans LH, Harrington LB, Greenwood-Hickman MA, Green BB, Psaty BM. Renin-angiotensin-aldosterone system inhibitors and COVID-19 infection or hospitalization: a cohort study. medRxiv. 2020:2020.07.06.20120386. doi: 10.1101/2020.07.06.20120386. PubMed
Williams EC, McGinnis KA, Rubinsky AD, Matson TE, Bobb JF, Lapham GT, Edelman EJ, Satre DD, Catz SL, Richards JE, Bryant KJ, Marshall BDL, Kraemer KL, Crystal S, Gordon AJ, Skanderson M, Fiellin DA, Justice AC, Bradley KA. Alcohol use and antiretroviral adherence among patients living with HIV: is change in alcohol use associated with change in adherence? AIDS Behav. 2021 Jan;25(1):203-214. doi: 10.1007/s10461-020-02950-x. PubMed
![]() Lisa A. Jackson, MD, MPHSenior Investigator |
![]() Jennifer C. Nelson, PhDDirector of Biostatistics; Senior Investigator |
![]() Michael L. Jackson, PhD, MPHSenior Investigator |
![]() Andrea J. Cook, PhDSenior Investigator |
![]() Sascha Dublin, MD, PhDSenior Investigator |
![]() Onchee Yu, MSBiostatistician III |
![]() Robert D. Wellman, MSBiostatistician III |
Doug Opel, MD, MPH
University of Washington (UW) Department of Bioethics and Humanities; UW Department of Pediatrics; UW Medical Center
John Dunn, MD, MPH
Kaiser Foundation Health Plan of Washington
Elizabeth Lin, MD, MPH
Kaiser Foundation Health Plan of Washington Family Practice;
Kaiser Permanente Washington Health Research Institute