Vaccines save lives by protecting people against infectious diseases—polio, influenza, and malaria to name a few. Kaiser Permanente Washington Health Research Institute (KPWHRI) is working to protect communities through research to continually improve the safety and effectiveness of vaccines and other treatments for infectious diseases as well as cancer. We also test new vaccines that may stop the threat of emerging diseases such as the novel coronavirus (SARS-CoV-2), which causes COVID-19.
Our research projects on vaccines and infectious diseases include:
Successes over 3 decades of KPWHRI research on vaccines and preventing and treating infectious disease include:
Dublin S, Walker R, Floyd JS, Shortreed SM, Fuller S, Albertson-Junkans L, Harrington LB, Greenwood-Hickman MA, Green BB, Psaty BM. Response to "ACE-2 downregulation and incidence of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection". Am J Hypertens. 2020 Dec 15:hpaa212. doi: 10.1093/ajh/hpaa212. [Epub ahead of print]. PubMed
Widge AT, Rouphael NG, Jackson LA, Anderson EJ, Roberts PC, Makhene M, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott AB, Flach B, Lin BC, Doria-Rose NA, O'Dell S, Schmidt SD, Neuzil KM, Bennett H, Leav B, Makowski M, Albert J, Cross K, Edara VV, Floyd K, Suthar MS, Buchanan W, Luke CJ, Ledgerwood JE, Mascola JR, Graham BS, Beigel JH; mRNA-1273 Study Group. Durability of responses after SARS-CoV-2 mRNA-1273 vaccination. N Engl J Med. 2020 Dec 3:NEJMc2032195. doi: 10.1056/NEJMc2032195. [Epub ahead of print]. PubMed
Newman KL, Rogers JH, McCulloch D, Wilcox N, Englund JA, Boeckh M, Uyeki TM, Jackson ML, Starita L, Hughes JP, Chu HY, Seattle Flu Study Investigators. Point-of-care molecular testing and antiviral treatment of influenza in residents of homeless shelters in Seattle, WA: study protocol for a stepped-wedge cluster-randomized controlled trial. Trials. 2020 Nov 23;21(1):956. doi: 10.1186/s13063-020-04871-5. PubMed
Emanuels A, Heimonen J, O’Hanlon J, Kim AE, Wilcox N, McCulloch DJ, Brandstetter E, Wolf CR, Logue JK, Han PD, Pfau B, Newman KL, Hughes JP, Jackson ML. Remote household observation for non-influenza respiratory viral illness. Clin Infect Dis. 2020 Nov 17:ciaa1719. doi: 10.1093/cid/ciaa1719. PubMed
Panagiotakopoulos L, McCarthy NL, Tepper NK, Kharbanda EO, Lipkind HS, Vazquez-Benitez G, McClure DL, Greenberg V, Getahun D, Glanz JM, Naleway AL, Klein NP, Nelson JC, Weintraub ES. Evaluating the association of stillbirths after maternal vaccination in the Vaccine Safety Datalink. Obstet Gynecol. 2020 Dec;136(6):1086-1094. doi: 10.1097/AOG.0000000000004166. PubMed
![]() Lisa A. Jackson, MD, MPHSenior Investigator |
![]() Jennifer C. Nelson, PhDDirector of Biostatistics; Senior Investigator |
![]() Michael L. Jackson, PhD, MPHSenior Investigator |
![]() Andrea J. Cook, PhDSenior Investigator |
![]() Sascha Dublin, MD, PhDSenior Investigator |
![]() Onchee Yu, MSBiostatistician III |
![]() Robert D. Wellman, MSBiostatistician III |
Doug Opel, MD, MPH
University of Washington (UW) Department of Bioethics and Humanities; UW Department of Pediatrics; UW Medical Center
John Dunn, MD, MPH
Kaiser Foundation Health Plan of Washington
Elizabeth Lin, MD, MPH
Kaiser Foundation Health Plan of Washington Family Practice;
Kaiser Permanente Washington Health Research Institute