Cancer is complex, so our researchers work to improve cancer control on many levels, from prevention and screening through treatment and survivorship. Kaiser Permanente Washington Health Research Institute (KPWHRI) was the first organization to develop and implement an evidence-based breast cancer screening program. This novel initiative used a computer-based registry before electronic health records (EHRs) existed. The program led to a rich portfolio of studies including on breast, colorectal, blood, cervical, lung, ovarian, and other cancer types. “Decades later,” says Karen Wernli, PhD, KPWHRI associate investigator, “Kaiser Permanente Washington is just as committed to developing and evaluating innovations in cancer care.”
The core of KPWHRI cancer research lies in its participation in many collaborative networks and programs. “Collaboration increases the power of Kaiser Permanente studies and helps us learn from different populations and health care settings,” says senior investigator Jessica Chubak, PhD. Examples of these networks include:
Marlow EC, Ducore J, Kwan ML, Cheng SY, Bowles EJA, Greenlee RT, Pole JD, Rahm AK, Stout NK, Weinmann S, Smith-Bindman R, Miglioretti DL. Leukemia risk in a cohort of 3.9 million children with and without Down syndrome. J Pediatr. 2021 Mar 5:S0022-3476(21)00212-2. doi: 10.1016/j.jpeds.2021.03.001. [Epub ahead of print]. PubMed
Makhnoon S, Bowen DJ, Shirts BH, Fullerton SM, Larson EB, Ralston JD, Leppig KA, Crosslin DR, Veenstra D, Jarvik GP. The FamilyTalk randomized controlled trial: patient-reported outcomes in clinical genetic sequencing for colorectal cancer. Cancer Causes Control. 2021 Feb 16. doi: 10.1007/s10552-021-01398-1. [Epub ahead of print]. PubMed
Lee CI, Zhu W, Onega T, Henderson LM, Kerlikowske K, Sprague BL, Rauscher GH, O'Meara ES, Tosteson ANA, Haas JS, diFlorio-Alexander R, Kaplan C, Miglioretti DL. Comparative Access to and Use of Digital Breast Tomosynthesis Screening by Women's Race/Ethnicity and Socioeconomic Status. JAMA Netw Open. 2021;4(2):e2037546. doi: 10.1001/jamanetworkopen.2020.37546. PubMed
Shay LA, Kimbel KJ, Dorsey CN, Jauregui LC, Vernon SW, Kullgren JT, Green BB. Patients' reactions to being offered financial incentives to increase colorectal screening: a qualitative analysis. Am J Health Promot. 2021 Jan 28:890117120987836. doi: 10.1177/0890117120987836. [Epub ahead of print]. PubMed
Farjah F, Monsell SE, Gould MK, Smith-Bindman R, Banegas MP, Heagerty PJ, Keast EM, Ramaprasan A, Schoen K, Brewer EG, Greenlee RT, Buist DSM. Association of the intensity of diagnostic evaluation with outcomes in incidentally detected lung nodules. JAMA Intern Med. 2021 Jan 19. doi: 10.1001/jamainternmed.2020.8250. Online ahead of print. PubMed
![]() Melissa L. Anderson, MSBiostatistician III |
![]() Denise M. Boudreau, PhDSenior Investigator |
![]() Erin J. Bowles, MPHResearch Associate |
![]() Diana S. Buist, PhD, MPHDirector of Research and Strategic Partnerships; Senior Investigator |
![]() David S. Carrell, PhDAssociate Investigator |
![]() Jessica Chubak, PhD, MBHLSenior Investigator |
![]() Yates Coley, PhDAssistant Investigator |
![]() Andrea J. Cook, PhDSenior Investigator |
![]() Marlaine Gray, PhDAssistant Investigator |
![]() Beverly B. Green, MD, MPHSenior Investigator |
![]() Nora Henrikson, PhD, MPHAssistant Investigator |
![]() Laura E. Ichikawa, MSBiostatistician III |
![]() Aruna Kamineni, PhD, MPHAssistant Investigator |
![]() Jennifer B. McClure, PhDDirector of Research, Faculty, & Development; Senior Investigator |
![]() Ellen O'Meara, PhDSenior Research Associate |
![]() Lorella Palazzo, PhDResearch Associate |
![]() Gaia Pocobelli, PhDResearch Associate |
![]() Leah Tuzzio, MPHSenior Research Associate |
![]() Rod L. Walker, MSBiostatistician III |
![]() Robert D. Wellman, MSBiostatistician III |
![]() Karen Wernli, PhDAssociate Investigator |
![]() Onchee Yu, MSBiostatistician III |
![]() Weiwei Zhu, MSBiostatistician III |
![]() Yu-Ru Su, PhDAssistant Investigator |
Wylie Burke, MD, PhD
University of Washington (UW) Department of Medical History and Ethics
Joann G. Elmore, MD, MPH
Harborview Medical Center; UW Department of Epidemiology
Larry Kessler, ScD
UW Department of Health Services
Constance D. Lehman, MD, PhD
Seattle Cancer Care Alliance; UW Department of Radiology
Kathy Leppig, MD
Kaiser Foundation Health Plan of Washington; UW Department of Pathology
Peggy L. Porter, MD
Fred Hutchinson Cancer Research Center (FHCRC); UW Department of Pathology
Emily White, PhD
FHCRC; UW Department of Epidemiology
Rachel Winer, PhD, MPH
Fred Hutchinson/UW Cancer Consortium; UW Department of Epidemiology