Americans are using more prescription drugs than ever. Consequently, they’re coping with more side effects, drug interactions, and costs, especially if they’re using multiple medications. Kaiser Permanente Washington Health Research Institute (KPWHRI) scientists are on the forefront of answering questions about these concerns. We’re studying the beneficial and harmful effects of medications in real-world settings, and innovating better ways to manage and monitor drug use.
The institute contributes to national initiatives to monitor medication safety as well as providing information to help doctors and patients weigh the risks and benefits of various prescription drugs.
Funders of KPWHRI medication use and patient safety research include the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, the National Institutes of Health, the Patient-Centered Outcomes Research Institute, and other sources. A few projects include:
Porta M, Jick H, Habakangas JS. Follow-up study of pseudoephedrine users. Ann Allergy. 1986;57(11):340-2. PubMed
Jick SS, Walker AM, Jick H. Conjugated estrogens and fibrocystic breast disease. Am J Epidemiol. 1986;124(5):746-51. PubMed
Beard K, Belic L, Aselton P, Perera DR, Jick H. Outpatient drug-induced parenchymal liver disease requiring hospitalization. J Clin Pharmacol. 1986;26(8):633-7. PubMed
Wohns RN, Colpitts M, Clement T, Karuza A, Blackett WB, Foutch R, Larson E. Phenytoin and acute mountain sickness on Mount Everest. Am J Med. 1986;80(1):32-6. PubMed
Jick H, Feld AD, Perera DR. Certain nonsteroidal anti-inflammatory drugs and hospitalization for upper gastrointestinal bleeding. Pharmacotherapy. 1985;5(5):280-4. PubMed
![]() Sascha Dublin, MD, PhDSenior Investigator |
![]() Jessica Chubak, PhDSenior Investigator |
![]() Andrea J. Cook, PhDSenior Biostatistics Investigator |
![]() Rita Mangione-Smith, MD, MPHVice President for Research and Health Care Innovation, Kaiser Permanente Washington; Executive Director and Senior Investigator, Kaiser Permanente Washington Health Research Institute |
![]() Eric B. Larson, MD, MPH, MACPSenior Investigator and former Executive Director, Kaiser Permanente Washington Health Research Institute; Former Vice President for Research and Health Care Innovation, Kaiser Permanente Washington |
![]() Jennifer C. Nelson, PhDDirector, Biostatistics; Senior Investigator |
![]() David E. Arterburn, MD, MPHSenior Investigator, KPWHRI; Physician, Washington Permanente Medical Group, Internal Medicine |
![]() Susan M. Shortreed, PhDSenior Biostatistics Investigator |
![]() Lisa A. Jackson, MD, MPHSenior Investigator |
![]() Karen Wernli, PhDAssociate Investigator |
![]() Onchee Yu, MSSenior Collaborative Biostatistician |
![]() Rod L. Walker, MSSenior Collaborative Biostatistician |
![]() Robert D. Wellman, MSSenior Collaborative Biostatistician |
![]() Gaia Pocobelli, PhDCollaborative Scientist |
![]() David S. Carrell, PhDAssociate Investigator |
![]() Laura Harrington, PhD, MPHAssistant Investigator |
![]() Jennifer F. Bobb, PhDAssociate Biostatistics Investigator |
![]() Weiwei Zhu, MSSenior Collaborative Biostatistician |
![]() Paige D. Wartko, PhD, MPHCollaborative Scientist |
![]() Maricela Cruz, PhDAssistant Biostatistics Investigator |
![]() Brian D. Williamson, PhDAssistant Biostatistics Investigator |
![]() Noorie Hyun, PhDAssistant Biostatistics Investigator |
Susan Heckbert, MD, PhD
University of Washington (UW) Department of Epidemiology; UW Cardiovascular Health Research Unit
David Siscovick, MD, MPH
UW Department of Medicine; UW Department of Epidemiology; UW Cardiovascular Health Research Unit
Leslie Spangler, PhD
Amgen