Laura E. Ichikawa, MS

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"KPWHRI provides a great opportunity to collaborate with multidisciplinary teams and provide biostatistical support to improve patient health."

Laura E. Ichikawa, MS

Senior Collaborative Biostatistician, Kaiser Permanente Washington Health Research Institute

Biography

With more than 25 years at Kaiser Permanente Washington Health Research Institute (KPWHRI), Laura Ichikawa, MS, is known for her analytical skills, attention to detail regarding study design and data management, and expertise in data visualization. Her experience includes observational studies, randomized controlled trials, case-control studies, and multisite analyses.

Ms. Ichikawa is primarily focused on breast cancer and women’s health. She is involved in two large, multisite National Cancer Institute-funded projects: the Statistical Coordinating Center for the Breast Cancer Surveillance Consortium (BCSC) and a colorectal research site for Population-based Research to Optimize the Screening Process (PROSPR). Much of her work with the BCSC has been evaluating mammography performance and use of other imaging modalities such as MRI, or magnetic resonance imaging, especially after a breast cancer diagnosis. Ms. Ichikawa also participated in collaborative research through the Cancer Research Network, including a widely publicized 2004 study that linked not having screening mammograms to late-stage breast cancer. More recently, this work examined the association of chemotherapy use with peripheral neuropathy. Ms. Ichikawa is excited to continue her work in breast cancer research, including in screening, treatment, surveillance, and survival.

Ms. Ichikawa's research with retired KPWHRI Senior Investigator Delia Scholes, PhD, includes studies examining bone loss associated with the injectable hormonal contraceptive Depo-Provera in 2002 and 2005 and oral contraceptives in 2011. She continues to work in areas of women’s health and contraceptive methods.

Ms. Ichikawa is a member of the American Statistical Association and its Puget Sound chapter.

Research interests and experience

  • Biostatistics

    Longitudinal data analysis

  • Cancer

    Biostatistics; breast cancer

  • Women's Health

    Biostatistics; hormonal contraception and bone density

 

Recent publications

Spangler L, Ichikawa LE, Hubbard RA, Operskalski B, LaCroix AZ, Ott SM, Scholes D. A comparison of self-reported oral contraceptive use and automated pharmacy data in perimenopausal and early postmenopausal women. Ann Epidemiol. 2015 Jan;25(1):55-9. doi: 10.1016/j.annepidem.2014.10.009. Epub 2014 Oct 16. PubMed

Wernli KJ, DeMartini WB, Ichikawa L, Lehman C, Onega TL, Kerlikowske K, Gellar BM, Hofmann M, Yankaskas BC; for the Breast Cancer Surveillance Consortium. Patterns of breast magnetic resonance imaging use in community practice. JAMA Intern Med. 2014 Jan;174(1):125-32. doi: 10.1001/jamainternmed.2013.11963. Epub 2013 Nov 18. PubMed

Carney PA, Parikh J, Sickles EA, Feig SA, Monsees B, Bassett LW, Smith RA, Rosenberg R, Ichikawa L, Wallace J, Tran K, Miglioretti DL. Diagnostic mammography: identifying minimally acceptable interpretive performance criteria. Radiology. 2013 May;267(2):359-67. doi: 10.1148/radiol.12121216. Epub 2013 Jan 7. PubMed

Gierach GL, Ichikawa L, Kerlikowske K, Brinton LA, Farhat GN, Vacek PM, Weaver DL, Schairer C, Taplin SH, Sherman ME. Relationship between mammographic density and breast cancer death in the Breast Cancer Surveillance Consortium. J Natl Cancer Inst. 2012;104(16):1218-27. Epub 2012 Aug 21. PubMed

Grafton J, Ott S, Endres J, Kratohvil C, Hubbard R, Ichikawa L, St John J, Operskalski B, Spangler L, Anderson J, Rillamas-Sun E, LaCroix A, Scholes D. Ps1-52: Charting the course: adjudicating fractures in network enrollees using the electronic medical record. Clin Med Res. 2012;10(3):165. PubMed

Rillamas-Sun E, Ichikawa L, LaCroix A, Ott S, Hubbard R, Spangler L, Scholes D. Ps2-28: The association of body composition indices and hormonal contraceptive use in adolescent and young adult women. Clin Med Res. 2012;10(3):186. PubMed

Spangler L, Grafton J, Ichikawa L, LaCroix A, Ott S, Hubbard R, Operskalski B, Anderson J, Kratohvil C, Endres J, Rillamas-Sun E, Scholes D. Ps2-29: Comparison of self-reported oral contraceptive use and automated prescription fills. Clin Med Res. 2012;10(3):186-7. PubMed

Geller BM, Ichikawa L, Miglioretti DL, Eastman D. Web-based mammography audit feedback. AJR Am J Roentgenol. 2012;198(6):W562-7. PubMed

Scholes D, Hubbard R, Ichikawa LE, LaCroix AZ, Spangler L, Beasley JM, Reed S, Ott SM. Oral contraceptive use and bone density change in adolescent and young adult women: a prospective study of age, hormone dose, and discontinuation. J Clin Endocrinol Metab. 2011 Sep;96(9):E1380-7. Epub 2011 Jul 13. PubMed

DeMartini WB, Ichikawa L, Yankaskas BC, Buist D, Kerlikowske K, Geller B, Onega T, Rosenberg RD, Lehman CD. Breast MRI in community practice: equipment and imaging techniques at facilities in the Breast Cancer Surveillance Consortium. J Am Coll Radiol. 2010;7(11):878-84. PubMed

 

Research

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IUD perforation: Rare but important to know about

New study results in more precise language in the federally mandated warning about this possibility.

cancer research

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Using breast MRI after cancer may lead to unneeded biopsies

A Kaiser Permanente-led BCSC study is among the largest ever to evaluate adding MRI surveillance for breast cancer survivors.

cancer screening

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No need to follow up simple ovarian cysts

New KPWHRI study shows that women with simple cysts are not at increased risk of ovarian cancer.

aging & geriatrics

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Study finds various treatments can reduce vaginal discomfort from sex

Dr. Katherine Newton co-wrote JAMA Internal Medicine paper comparing vaginal estrogen, moisturizer, and placebo gel.